1434589-24-8Relevant articles and documents
Synthesis of phosphinodepsipeptides via the pseudo-four-component condensation reaction
Meng, Fanhua,Xu, Jiaxi
, p. 4944 - 4952 (2013/07/19)
Phosphinodepsipeptides are recognized as an important class of enzyme inhibitors as tetrahedrally structural transition-state analogues to natural peptides. A series of phosphinodepsipeptides was synthesized in satisfactory yields via pseudo-four-component condensation reaction of 2-(N- benzoxycarbonylamino)alkanamides/peptide amides, aldehydes, and aryldichlorophosphines, followed by alcoholysis with hydroxyl esters.