143468-07-9 Usage
Molecular Structure
1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 6-chloro-, methyl ester is a chemical compound with a unique molecular structure that features a pyrrolopyridine ring system and a carboxyl group.
Functional Groups
The carboxyl group and the methyl ester group are the two main functional groups present in this compound, which contribute to its reactivity and properties.
Molecular Weight
The molecular weight of 1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 6-chloro-, methyl ester is [Molecular Weight].
Physical State
This compound is a solid at room temperature.
Solubility
1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 6-chloro-, methyl ester is soluble in [Solvent 1], [Solvent 2], and [Solvent 3], but insoluble in [Solvent 4].
Chemical Reactivity
This compound is reactive towards [Reagent 1], [Reagent 2], and [Reagent 3]. It can undergo [Reaction 1], [Reaction 2], and [Reaction 3] to form various derivatives.
Pharmaceutical Applications
1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 6-chloro-, methyl ester is commonly used as an intermediate in the synthesis of various pharmaceutical drugs and as a building block in the development of new drug candidates for the treatment of various medical conditions.
Safety and Handling
This compound should be handled with care and proper safety measures, as it may be toxic or hazardous under certain conditions. It should be stored in a [Storage Condition].
Check Digit Verification of cas no
The CAS Registry Mumber 143468-07-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,4,6 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 143468-07:
(8*1)+(7*4)+(6*3)+(5*4)+(4*6)+(3*8)+(2*0)+(1*7)=129
129 % 10 = 9
So 143468-07-9 is a valid CAS Registry Number.
143468-07-9Relevant articles and documents
Synthesis of new substituted 2-(trimethylstannyl)indoles
Kumar, Arvind,Say, Martial,Boykin, David W.
, p. 707 - 710 (2008)
Synthesis of the previously unreported 2-(trimethylstannyl)indole derivatives, 5-bromo-1-(tert-butoxycarbonyl)-2-(trimethylstannyl)-1H-indole, 6-bromo-1-(tert-butoxycarbonyl)-2-(trimethylstannyl)-1H-indole, 1-(tert-butoxycarbonyl)-2-(trimethylstannyl)-1H-indole-5-carbonitrile, 1-(tert-butoxycarbonyl)-2-(trimethylstannyl)-1H-indole-6-carbonitrile and 1-(tert-butoxycarbonyl)-2-(trimethylstannyl)-1H-pyrrolo[2,3-b] pyridine-6-carbonitrile, is described. Georg Thieme Verlag Stuttgart.
NEW CRTH2 ANTAGONISTS
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Page/Page column 137, (2013/03/26)
The present invention relates to compounds of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by CRTh2 antagonist activity.
Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents
Tung, Yen-Shih,Coumar, Mohane Selvaraj,Wu, Yu-Shan,Shiao, Hui-Yi,Chang, Jang-Yang,Liou, Jing-Ping,Shukla, Paritosh,Chang, Chun-Wei,Chang, Chi-Yen,Kuo, Ching-Chuan,Yeh, Teng-Kuang,Lin, Chin-Yu,Wu, Jian-Sung,Wu, Su-Ying,Liao, Chun-Chen,Hsieh, Hsing-Pang
scheme or table, p. 3076 - 3080 (2011/06/25)
Utilizing scaffold-hopping drug-design strategy, we sought to identify a backup drug candidate for BPR0L075 (1), an indole-based anticancer agent. For this purpose, 5,6-fused bicyclic heteroaromatic scaffolds were designed and synthesized through shufflin
