144-02-5 Usage
Description
5,5-Diethylbarbituric acid sodium salt, also known as the monosodium salt of barbital, is a long-acting barbiturate that possesses the ability to depress most metabolic processes at high doses. It is characterized by its bitter taste and appears as crystals or powder.
Uses
Used in Pharmaceutical Industry:
5,5-Diethylbarbituric acid sodium salt is used as a sedative and hypnotic agent for its ability to depress metabolic processes at high doses, making it a valuable component in the development of medications aimed at inducing sleep or reducing anxiety.
Used in Research and Development:
In the field of research and development, 5,5-Diethylbarbituric acid sodium salt is utilized as a biological buffer due to its soluble nature, allowing for its application in various experimental procedures and assays that require stable pH conditions.
Used in Chemical Synthesis:
5,5-Diethylbarbituric acid sodium salt is also employed as an intermediate in the synthesis of other barbiturate derivatives, contributing to the development of a diverse range of pharmaceutical compounds with potential applications in medicine and other industries.
Hazard
Poison; causes marked depression, pro-
longed coma, and death; teratogen; questionable
carcinogen; tumorigen; neoplastigen; mutagen.
Flammability and Explosibility
Notclassified
Safety Profile
Poison by ingestion,
subcutaneous, intravenous, and
intraperitoneal routes. Large doses cause
marked depression (sometimes preceded by
excitation), prolonged coma, and death.
Experimental teratogenic and reproductive
effects. Allergic skin reactions may occur on
contact. Implicated in development of
aplastic anemia. Questionable carcinogin with experimental tumorigenic and
neoplastigenic data. A truly habit-forming
drug. Other experimental reproductive
effects. Mutation data reported.
Combustible. When heated to
decomposition it emits toxic fumes of NO,
and NazO. See also BARBITURATES
Purification Methods
Crystallise it from water (3mL/g) by adding an equal volume of EtOH and cooling to 5o. Dry it under vacuum over P2O5. [Beilstein 24 III/IV 1904.]
Check Digit Verification of cas no
The CAS Registry Mumber 144-02-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 144-02:
(5*1)+(4*4)+(3*4)+(2*0)+(1*2)=35
35 % 10 = 5
So 144-02-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H12N2O3.Na/c1-3-8(4-2)5(11)9-7(13)10-6(8)12;/h3-4H2,1-2H3,(H2,9,10,11,12,13);/q;+1/p-1
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