144-74-1 Usage
Description
Sulfathiazole sodium is a sulfonamide antibiotic with a chemical structure that allows it to act as a competitive inhibitor of bacterial para-aminobenzoic acid (PABA). It is widely used in the medical field for its antimicrobial properties and is also utilized in various research applications.
Uses
1. Used in Medical Applications:
Sulfathiazole sodium is used as an antimicrobial agent for treating bacterial infections. It works by inhibiting the synthesis of folic acid in bacteria, which is essential for their growth and reproduction.
2. Used in Biological Studies:
Sulfathiazole sodium is used as a research tool in the study of thermotherapy and sulfonamide antibiotics. It helps researchers understand the mechanisms of action and resistance development in bacteria.
3. Used in Microbiome Research:
Sulfathiazole sodium is employed in the deciphering of Cyanobacteria and Proteobacteria microbiomes in huanglongbing-affected Citrus paradise and Citrus limon. This application aids in understanding the impact of these bacteria on the health of citrus plants and the potential role of sulfathiazole sodium in managing such infections.
Biochem/physiol Actions
Sulfathiazole is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfathiazole is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 144-74-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 144-74:
(5*1)+(4*4)+(3*4)+(2*7)+(1*4)=51
51 % 10 = 1
So 144-74-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N3O2S2.Na/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;/h1-6H,10H2;/q-1;+1
144-74-1Relevant articles and documents
Process for formulating a synthetic drug for use in animal feed, and resulting formulation
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, (2008/06/13)
A method of formulating a synthetic drug for use in animal feed, for the purpose of reducing carry-over of the synthetic drug to subsequent lots of animal feed in the feed mill.