1440537-79-0Relevant articles and documents
Synthesis of Terminal N-Vinylazoles from Aromatic Aldehydes, DMSO, and Azoles Based DMSO as Terminal Carbon Synthon
Nie, Zhiwen,Lv, Huifang,Li, Hui,Su, Miaodong,Yang, Tonglin,Luo, Weiping,Liu, Qiang,Guo, Cancheng
, p. 4621 - 4626 (2021/09/02)
A protocol for the synthesis of terminal N-vinylazoles from aromatic aldehydes, DMSO, and azoles has been reported. In this strategy, DMSO was involved in the construction of the C=C bond as a terminal carbon synthon. Both aromatic aldehydes and azoles could be well tolerated and give the corresponding terminal N-vinylazoles in 52–91% yields. Based on preliminary experiments, a plausible mechanism is proposed. (Figure presented.).