75230-51-2

Basic information

• Product Name: 4-bromoacetophenone tosylhydrazone
• Synonyms: 4-bromoacetophenone tosylhydrazone
• CAS NO: 75230-51-2
• Molecular Weight: 367.266
• Mol File: 75230-51-2.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: 4-bromoacetophenone tosylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromoacetophenone tosylhydrazone(75230-51-2)
• EPA Substance Registry System: 4-bromoacetophenone tosylhydrazone(75230-51-2)

Safety Data

• Hazardous Substances Data: 75230-51-2(Hazardous Substances Data)

Upstream product

• 99-90-1 para-bromoacetophenone 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 98-59-9 p-toluenesulfonyl chloride 
• 89108-50-9 1-(1-azidovinyl)-4-bromobenzene 

Downstream Products

• 66751-80-2 1-(4-bromophenyl)diazoethane 
• 99-90-1 para-bromoacetophenone 
• 1402745-83-8 5-(4-bromophenyl)-5-hexen-2-one 
• 56913-50-9 1-(4-bromophenyl)-1-phenylethane 
• 1414261-77-0 1-bromo-4-(1-p-tolylethyl)benzene 
• 1414261-80-5 1-(1-(4-bromophenyl)ethyl)-2-methylbenzene 
• 1418093-11-4 C₂₀H₁₈BrOP 
• 1429337-90-5 benzoyl(2-(1-(4-bromophenyl)ethyl)pyridinium-1-yl)azanide 
• 1440537-79-0 1-(1-(4-bromophenyl)vinyl)-1H-indole 
• 101422-65-5 2-[1-(4-bromophenyl)ethyl]isoindoline-1,3-dione 
• 24358-62-1 1-(4-bromophenyl)ethylamine 

Relevant articles and documents

One-pot synthesis of sulfonylhydrazones from sulfonyl chloride, hydrazine hydrate and vinyl azide in water

A facile and eco-friendly protocol for the synthesis of sulfonylhydrazones from sulfonyl chlorides, hydrazine hydrate and vinyl azides was developed. The unique advantage of this approach is that desired products can be obtained efficiently in water, which meets the requirements of green chemistry and provides good perspectives for the sustainable production of new drug candidate. Also, this reaction proceeded in moderate to good yields with a wide tolerance of functional groups.

Copper(I)/Bpy-Catalyzed C-2-H Benzylation of Quinazolin-4(3H)-ones with N-Tosylhydrazones

A general and efficient copper-catalyzed C–H benzylation reaction of quinazolin-4(3H)-ones with N-tosylhydrazones is reported. The formation of new C(sp3)–C(sp2) bonds through cross-coupling occurs at the electron-poor C-2 position of quinazolin-4(3H)-one and represents an exceedingly practical method to afford 2-benzylated quinazolin-4(3H)-ones in moderate to good yields under mild reaction conditions. A possible reaction mechanism for this transformation was proposed. This catalytic transformation has the potential to be an important synthetic application for the late-stage functionalization of advanced synthetic intermediates.

I2-Promoted [4 + 2] cycloaddition of: In situ generated azoalkenes with enaminones: Facile and efficient synthesis of 1,4-dihydropyridazines and pyridazines

A facile and efficient strategy for the synthesis of 1,4-dihydropyridazines and pyridazines through I2-promoted [4 + 2] cycloaddition of in situ generated azoalkenes with enaminones has been developed. The switch in selectivity is attributed to the judici