144121-60-8

Basic information

• Product Name: Benzenemethanol, a-4-pentenyl-, (S)-
• CAS NO: 144121-60-8
• Molecular Formula: C12H16O
• Molecular Weight: 176.258
• Mol File: 144121-60-8.mol
• Article Data: 40

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-4-pentenyl-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-4-pentenyl-, (S)-(144121-60-8)
• EPA Substance Registry System: Benzenemethanol, a-4-pentenyl-, (S)-(144121-60-8)

Safety Data

• Hazardous Substances Data: 144121-60-8(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 1119-51-3 bromopentene 
• 4285-51-2 pent-4-en-1-yl phenyl sulfide 
• 67-56-1 methanol 
• 138971-29-6 Phosphoric acid diethyl ester 1-phenyl-hex-5-enyl ester 
• 821-41-0 5-Hexen-1-ol 
• 98-80-6 phenylboronic acid 
• 20780-53-4 (R)-Styrene oxide 
• 7103-09-5 4-but-1-enylmagnesium bromide 
• 108-05-4 vinyl acetate 
• 144121-60-8 1-phenylhex-5-en-1-ol 
• 104-53-0 3-phenyl-propionaldehyde 
• 33651-13-7 (1R,2S,5R)-1-allyl-2-isopropyl-5-methylcyclohexanol 
• 34164-50-6 4-penten-1-ylmagnesium bromide 

Downstream Products

• 61608-88-6 (1-chlorohex-5-en-1-yl)benzene 
• 38383-05-0 6-bromo-6-phenyl-1-hexene 
• 190730-15-5 5-Iodo-1-phenyl-6-(toluene-4-sulfonyl)-hexan-1-ol 
• 22524-25-0 1-phenylhex-5-en-1-one 
• 1009-81-0 1,5-hexadien-1-yl-benzene 
• 1393380-70-5 C₁₄H₁₈O₂ 
• 65727-70-0 (R)-1-phenylhex-5-en-1-ol 
• 65727-70-0 (-)-1-Phenylhex-5-en-1-ol 
• 1610543-21-9 C₁₃H₁₈O 
• 1610543-76-4 C₁₂H₁₆O₂ 
• 1610543-60-6 C₁₂H₁₄ 
• 1610543-74-2 C₁₂H₁₆O₂ 

Relevant articles and documents

Lithium or Bromomagnesium 1,4- and 1,5-Dilithioalkan-2-yloxides: Preparation and Synthetic Applications

Treatment of chloromethyl 2- or 3-chloroalkyl carbinols with butyllithium and then lithium naphthalenide or with ethylmagnesium bromide and then powdered lithium leads to the formation of lithium or bromomagnesium dilithiothioalkoxides, respectively, which represent trianionic species.The bromomagnesium 1,ω-dilithio-2-alkoxides undergo immediate elimination of lithium bromide and magnesium oxide to give ω-lithio-1-alkenes.These latter organometallic compounds as well as the lithium dithioalkoxides react with various electrophiles to afford functionalized compounds.

Selective Synthesis of Z-Silyl Enol Ethers via Ni-Catalyzed Remote Functionalization of Ketones

We report a remote functionalization strategy, which allows the Z-selective synthesis of silyl enol ethers of (hetero)aromatic and aliphatic ketones via Ni-catalyzed chain walking from a distant olefin site. The positional selectivity is controlled by the directionality of the chain walk and is independent of thermodynamic preferences of the resulting silyl enol ether. Our mechanistic data indicate that a Ni(I) dimer is formed under these conditions, which serves as a catalyst resting state and, upon reaction with an alkyl bromide, is converted to [Ni(II)-H] as an active chain-walking/functionalization catalyst, ultimately generating a stabilized η3-bound Ni(II) enolate as the key selectivity-controlling intermediate.

Rhodium-Catalyzed Remote Isomerization of Alkenyl Alcohols to Ketones

We develop herein an efficient rhodium-catalyzed remote isomerization of aromatic and aliphatic alkenyl alcohols into ketones. This catalytic process, with a commercially available catalyst and ligand ([RhCl(cod)]2 and Xantphos), features high efficiency, low catalyst loading, good functional group tolerance, a broad substrate scope, and no (sub)stoichiometric additive. Preliminary mechanistic studies suggest that this transformation involves an iterative dissociative β-hydride elimination-migration insertion process.