1443467-88-6

Basic information

• Product Name: 1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester
• Synonyms: 1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester
• CAS NO: 1443467-88-6
• Molecular Weight: 354.444
• Mol File: 1443467-88-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester(1443467-88-6)
• EPA Substance Registry System: 1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester(1443467-88-6)

Safety Data

• Hazardous Substances Data: 1443467-88-6(Hazardous Substances Data)

Usage

Description

1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester is a complex organic molecule characterized by its unique structure, which includes a phenyl group, multiple ester and ether linkages, and a tert-butyl ester group. This molecule is notable for its potential applications in various fields due to its structural properties.

Uses

Used in Pharmaceutical Industry:
1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester is used as a pharmaceutical compound for its potential therapeutic applications. The molecule's unique structure allows it to interact with specific biological targets, making it a candidate for the development of new drugs.
Used in Chemical Synthesis:
In the field of chemical synthesis, 1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester serves as a key intermediate or building block for the creation of more complex molecules. Its versatile structure and functional groups make it a valuable component in the synthesis of various compounds.
Used in Material Science:
1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester is used as a component in the development of new materials. Its structural properties may contribute to the creation of materials with unique characteristics, such as improved stability, enhanced solubility, or specific interactions with other molecules.
Used in Research and Development:
This molecule is also utilized in research and development settings, where it can be studied to better understand its properties and potential applications. Researchers may use 1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester to explore new reaction pathways, investigate its interactions with biological systems, or develop new methods for its synthesis.
Overall, 1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester is a versatile molecule with a wide range of potential applications across various industries, including pharmaceuticals, chemical synthesis, material science, and research and development. Its unique structure and functional groups make it an interesting candidate for further exploration and utilization.

Upstream product

• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 55489-58-2 triethylene glycol monobenzyl ether 

Downstream Products

• 1618678-45-7 (2S,4R)-1-((S)-2-(tert-butyl)-14-(4-(5-((7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)pentyl)piperazin-1-yl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 
• 1530778-24-5 t-butyl [2-(2-{2-[(4-methylbenzene-1-sulfonyl)oxy]ethoxy}ethoxy)ethoxy]acetate 
• 518044-31-0 tert-butyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate 
• 1618678-46-8 (2S,4R)-1-((S)-2-(tert-butyl)-20-((7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-15-methyl-4-oxo-6,9,12-trioxa-3,15-diazaicosan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 
• 1443467-90-0 N-(6-(5-(1,2-dithiolan-3-yl)pentanamido)hexyl)-1-phenyl-2,5,8,11-tetraoxatridecan-13-amide 

Relevant articles and documents

Heterocyclic compound and application thereof

The invention discloses a heterocyclic compound and application thereof. The invention provides a heterocyclic compound as shown in a formula I, or pharmaceutically acceptable salt thereof. The heterocyclic compound can be used for degrading ALK, c-Met and ROS proteins.

Compound for targeted degradation of ALK, c-Met and ROS1 proteins, and preparation method thereof

The invention provides a novel compound for targeted degradation of ALK, c-Met and ROS1 proteins, wherein the compound is represented by a formula A, is formed by linking an ubiquitin ligase E3 recognition ligand and an ALK, c-Met and ROS1 protein inhibitor compound through a linking arm, and can selectively induce degradation of ALK, c-Met and ROS1 proteins and mutant proteins of the ALK, c-Met and ROS1 proteins. According to the invention, a bifunctional small molecule is obtained; and in-vitro anti-tumor activity data of the compound show that the compound has high-efficiency anti-tumor activity on conventional tumor cells, has strong inhibition activity on mutant cell strains (BaF3/EML4-ALKG1202R, BaF3/EML4-ALKL1196M and BaF3-TEL-ALK-C1156Y) causing the drug resistance, provides a effective antitumor drug for clinical application, has great application value, brings good news for tumor treatment, especially for some drug-resistant patients, and has important social benefits.

NOVEL COMPOUNDS

A compound of formula (I): or a pharmaceutically acceptable salt thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, comp