55489-58-2

Basic information

• Product Name: Triethylene glycol monobenzyl ether
• Synonyms: 2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHANOL;RARECHEM AH CK 0201;TRIETHYLENEGLYCOLMONOBENZYL ETHER;TEGmonobenzylether;TRIETHYLENEGLYKOLMONOBENZYLETHER;2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethan-1-ol;Triethyleneglycolmonobenzylether97%;BnO-PEG3-OH
• CAS NO: 55489-58-2
• Molecular Formula: C₁₃H₂₀O₄
• Molecular Weight: 240.3
• Product Categories: Ethylene Glycols & Monofunctional Ethylene Glycols;Monofunctional Ethylene Glycols
• Mol File: 55489-58-2.mol
• Article Data: 42

Chemical Properties

• Boiling Point: 131 °C
• Flash Point: 170.3 °C
• Appearance: /
• Density: 1.09
• Vapor Pressure: 9.53E-06mmHg at 25°C
• Refractive Index: 1.5050 to 1.5080
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.36±0.10(Predicted)
• CAS DataBase Reference: Triethylene glycol monobenzyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: Triethylene glycol monobenzyl ether(55489-58-2)
• EPA Substance Registry System: Triethylene glycol monobenzyl ether(55489-58-2)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 55489-58-2(Hazardous Substances Data)

Usage

Description

Triethylene glycol monobenzyl ether, also known as Benzyl-PEG4-alcohol, is a PEG (polyethylene glycol) linker with an acid-labile benzyl protecting group and a reactive primary alcohol. The primary alcohol allows for further derivatization of the compound, while the hydrophilic PEG linker enhances its water solubility in aqueous media.

Uses

Used in Biosensor Applications:
Triethylene glycol monobenzyl ether is used as a component in the preparation of self-assembled monolayers with multiple binding sites and biocompatible imprinted cavities, which are essential for the development of biosensors. The hydrophilic PEG linker contributes to the stability and performance of these biosensors in aqueous environments.
Used in Surfactant Synthesis:
In the chemical industry, Triethylene glycol monobenzyl ether is utilized in the synthesis of novel ethoxylated inositol surfactants. These surfactants have various applications, including detergents, emulsifiers, and stabilizers in the formulation of personal care products, pharmaceuticals, and other industrial products. The presence of the PEG linker and benzyl protecting group in Triethylene glycol monobenzyl ether plays a crucial role in the properties and performance of the resulting surfactants.

InChI:InChI=1/C13H20O4/c14-6-7-15-8-9-16-10-11-17-12-13-4-2-1-3-5-13/h1-5,14H,6-12H2

Upstream product

• 100-51-6 benzyl alcohol 
• 55791-06-5 benzyl mesylate 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 112-60-7 Tetraethylene glycol 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 75-21-8 oxirane 

Downstream Products

• 702701-70-0 methanesulfonic acid 2-[2-(2-benzyloxy-ethoxy)-ethoxy]-ethyl ester 
• 1618678-45-7 (2S,4R)-1-((S)-2-(tert-butyl)-14-(4-(5-((7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)pentyl)piperazin-1-yl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 
• 1530778-24-5 t-butyl [2-(2-{2-[(4-methylbenzene-1-sulfonyl)oxy]ethoxy}ethoxy)ethoxy]acetate 
• 518044-31-0 tert-butyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate 
• 1618678-48-0 (2S,4R)-1-((S)-2-(tert-butyl)-19-((7R,8R,9S,13S,14S,17S)-3-hydroxy-17-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-4-oxo-6,9,12,15-tetraoxa-3-azanonadecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 
• 1618678-63-9 15-((7R,8R,9S,13S,14S,17S)-17-methoxy-3-(methoxymethoxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-1-phenyl-2,5,8,11-tetraoxapentadecane 
• 1618678-62-8 (7R,8R,9S,13S,14S,17S)-13-methyl-7-(1-phenyl-2,5,8,11-tetraoxapentadecan-15-yl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3,17-diol 
• 1618678-47-9 (2S,4R)-1-((S)-2-(tert-butyl)-19-((7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-4-oxo-6,9,12,15-tetraoxa-3-azanonadecan-1-oyl)-N-(4-(2,4-dimethylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide 
• 1618678-46-8 (2S,4R)-1-((S)-2-(tert-butyl)-20-((7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-15-methyl-4-oxo-6,9,12-trioxa-3,15-diazaicosan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 
• 1448190-16-6 15-bromo-1-phenyl-2,5,8,11-tetraoxapentadecane 
• 1448190-17-7 15-iodo-1-phenyl-2,5,8,11-tetraoxapentadecane 
• 1443467-88-6 1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid tert-butyl ester 
• 1443467-90-0 N-(6-(5-(1,2-dithiolan-3-yl)pentanamido)hexyl)-1-phenyl-2,5,8,11-tetraoxatridecan-13-amide 
• 144751-75-7 1-phenyl-2,5,8,11-tetraoxatridecan-13-oic acid 

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