1445797-07-8

Basic information

• Product Name: 4-amino-2-chloro-N-[4-(4-methoxyphenyl)tetrahydropyran-4-ylmethyl]benzamide
• Synonyms: 4-amino-2-chloro-N-[4-(4-methoxyphenyl)tetrahydropyran-4-ylmethyl]benzamide
• CAS NO: 1445797-07-8
• Molecular Weight: 374.867
• Mol File: 1445797-07-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-amino-2-chloro-N-[4-(4-methoxyphenyl)tetrahydropyran-4-ylmethyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-2-chloro-N-[4-(4-methoxyphenyl)tetrahydropyran-4-ylmethyl]benzamide(1445797-07-8)
• EPA Substance Registry System: 4-amino-2-chloro-N-[4-(4-methoxyphenyl)tetrahydropyran-4-ylmethyl]benzamide(1445797-07-8)

Safety Data

• Hazardous Substances Data: 1445797-07-8(Hazardous Substances Data)

Upstream product

• 440087-51-4 1-[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]-methylamine 
• 16017-69-9 ethyl-2-chloro-4-amino-benzoate 
• 2457-76-3 4-amino-2-chlorobenzoic acid 

Downstream Products

• 1445797-05-6 5-methyl-[1,3,4]oxadiazole-2-carboxylic acid (3-chloro-4-{[4-(4-methoxyphenyl)tetrahydropyran-4-ylmethyl]carbamoyl}phenyl)amide 
• 1445797-06-7 C₂₅H₂₆ClN₃O₅ 

Relevant articles and documents

WNT PATHWAY INHIBITORS

Wnt pathway inhibitors A class of compounds having general formula (I) has been identified. These compounds function as inhibitors of the Wnt pathway. Compounds of formula (I) are suitable for the treatment and/or prevention of any condition or disease in which it is desirable to inhibit signaling in the Wnt pathway, in particular inhibiting the proliferation of tumor cells, especially those associated with breast cancer, non-small cell lung cancer, pancreatic and colorectal cancers (e.g. colon carcinoma cells). The compounds also find use in methods of preventing metastasis and methods of promoting and/or directing cellular differentiation of progenitor cells.