14467-32-4Relevant articles and documents
Asymmetric Reduction of α-Ketoimines with Oxazaborolidine Catalysts: A Novel, Practical Approach to Chiral Arylethanolamines
Hong, Yaping,Gao, Yun,Nie, Xiaoyi,Zepp, Charles M.
, p. 5551 - 5554 (1994)
Asymmetric borane reduction of α-ketoimines with oxazaborolidine catalysts has been studied.The ee's of the resulting arylethanolamines are uo to 93percent using 20 molpercent of the catalyst.
Efficient Synthesis of 2-Amino-1-Arylethanols Through a Lewis Base-Catalyzed SiCl4-Mediated Asymmetric Passerini-Type Reaction
Ayad, Tahar,Gernet, Aurélie,Pirat, Jean-Luc,Ratovelomanana-Vidal, Virginie,Virieux, David
supporting information, p. 6497 - 6500 (2020/10/30)
We herein report, a practical and efficient strategy for the synthesis of enantiomerically enriched 2-amino-1-arylethanols, a structural motif commonly encountered in the family of β-adrenergic blockers or agonists, through a Lewis base-catalyzed SiClsub
Method for Ir/f-amphox high-efficiency synthesis of chiral α- C-amino alcohol by virtue of catalytic oxidation 1,2- of P-aminoketone by using one-aminoketone
-
Paragraph 0064-0066, (2020/01/03)
The invention discloses a method for efficiently synthesizing chiral 1,2-amino alcohol by catalyzing alpha-aminoketone through Ir/f-amphox. A ligand f-amphox used by the method can be more easily synthesized; the reaction has the characteristics of enanti