144688-73-3

Basic information

• Product Name: 1-Pyrrolidinecarboxylic acid, 2-cyano-2-methyl-, 1,1-dimethylethyl ester
• CAS NO: 144688-73-3
• Molecular Formula: C11H18N2O2
• Molecular Weight: 210.276
• Mol File: 144688-73-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Pyrrolidinecarboxylic acid, 2-cyano-2-methyl-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylic acid, 2-cyano-2-methyl-, 1,1-dimethylethyl ester(144688-73-3)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylic acid, 2-cyano-2-methyl-, 1,1-dimethylethyl ester(144688-73-3)

Safety Data

• Hazardous Substances Data: 144688-73-3(Hazardous Substances Data)

Upstream product

• 86953-79-9 tert-butyl pyrrolidine-1-carboxylate 

Downstream Products

• 1312454-79-7 tert-butyl 2-(aminomethyl)-2-methylpyrrolidine-1-carboxylate 
• 132235-42-8 (2R)-2-methyl-2-pyrrolidinecarboxamide 
• 42856-71-3 (S)-2-methylpyrrolidine-2-carboxylic acid 

Relevant articles and documents

Electroorganic chemistry 139. Electroreductive decyanation of nitriles and its application to synthesis of α-alkylamines

Electroreduction of nitriles gave the corresponding decyanated products when Zn was used as the material of cathode in aprotic solvent (DMF or MeCN) containing Et4NOTs as a supporting electrolyte. Alkylation of amines at the α-position was effectively achieved by cyanation of amines at the α-position, and α-alkylation of the resultant α-amino nitriles followed by the electroreductive decyanation.