1449-09-8 Usage
Description
24-Methylene cycloartanol, also known as 24-Methylenecycloartan-3-ol (CAS# 1449-09-8), is a cyclized intermediate derived from 2,3-oxidosqualene in the biosynthetic pathway of phytosterols. It plays a significant role in the formation of steroid skeletons and holds potential chemotherapeutic importance.
Uses
Used in Pharmaceutical Industry:
24-Methylene cycloartanol is used as a chemotherapeutic agent for its antihyperlipemic properties. It helps in the treatment and management of conditions related to high levels of lipids in the blood, such as hyperlipidemia, by regulating the synthesis of cholesterol and other lipids.
Additionally, due to its structural similarity to steroids, 24-methylene cycloartanol may also be utilized in the development of other pharmaceutical compounds targeting various health conditions related to steroid hormone imbalances or deficiencies.
Check Digit Verification of cas no
The CAS Registry Mumber 1449-09-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,4 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1449-09:
(6*1)+(5*4)+(4*4)+(3*9)+(2*0)+(1*9)=78
78 % 10 = 8
So 1449-09-8 is a valid CAS Registry Number.
InChI:InChI=1/C31H52O/c1-20(2)21(3)9-10-22(4)23-13-15-29(8)25-12-11-24-27(5,6)26(32)14-16-30(24)19-31(25,30)18-17-28(23,29)7/h20,22-26,32H,3,9-19H2,1-2,4-8H3/t22-,23-,24+,25+,26+,28-,29+,30-,31+/m1/s1
1449-09-8Relevant articles and documents
DRUGS, FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS
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Page/Page column 14, (2008/06/13)
Compounds having a cyclolanostane skeleton such as 9,19-cyclolanostan-3-ol and 24-methylene-9,19-cyclolanostan-3-ol are used as an active ingredient of a drug and food or drink for improving pancreatic functions.
Conformational Analysis of Cycloartenol, 24-Methylenecycloartanol and Their Derivatives
Yoshida, Kumi,Hirose, Yoshihiko,Imai, Yutaka,Kondo, Tadao
, p. 1901 - 1912 (2007/10/02)
A conformational analysis of cycloartenol, 24-methylenecycloartenol and their derivatives was carried out in the solution and the solid state by an NMR study and X-ray crystallographic analysis, respectively.Complete assignments of the 1H NMR spectra of these compounds were made in order to elucidate the conformation involving the ring system and side chain.Rings A to C had a chair-halfchair-boat conformation, and the side chain had a zig-zag conformation.