1449306-19-7

Basic information

• Product Name: methyl 5-methoxy-2-[(1E,3Z)-3-(5-fluoro-1,3-dimethyl-2-oxo-1,3-dihydropyrimidin-4-ylidene)-1-propenyl]benzoate
• CAS NO: 1449306-19-7
• Molecular Weight: 346.358
• Mol File: 1449306-19-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 5-methoxy-2-[(1E,3Z)-3-(5-fluoro-1,3-dimethyl-2-oxo-1,3-dihydropyrimidin-4-ylidene)-1-propenyl]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-methoxy-2-[(1E,3Z)-3-(5-fluoro-1,3-dimethyl-2-oxo-1,3-dihydropyrimidin-4-ylidene)-1-propenyl]benzoate(1449306-19-7)
• EPA Substance Registry System: methyl 5-methoxy-2-[(1E,3Z)-3-(5-fluoro-1,3-dimethyl-2-oxo-1,3-dihydropyrimidin-4-ylidene)-1-propenyl]benzoate(1449306-19-7)

Safety Data

• Hazardous Substances Data: 1449306-19-7(Hazardous Substances Data)

Upstream product

• 5309-18-2 1,7-dimethoxynaphthalene 
• 3013-92-1 1,3-dimethyl-5-fluorouracil 

Relevant articles and documents

New results on the photoreactivity of 5-fluoro-1,3-dimethyluracil with methoxylated naphthalenes

Photocycloaddition of 5-fluoro-1,3-dimethyluracil (5-FDMU) with various methoxy and dimethoxynaphthalenes was investigated. Reaction of 5-FDMU with 1,x-dimethoxynaphthalenes (x = 4-7) gave rise to the selective formation of cycloadducts, conjugated arylpropenylidene-1,3-diazin-2-ones, which were derived from an initially formed oxetane moiety via the Paterno-Buechi reaction cycloadduct. The present study shows that the presence of a methoxy substituent on the ?-position in naphthalene is essential for the formation of products through the Paterno-Buechi reaction. This unique photoreaction involving formation of an oxetane between 5-FDMU and a naphthalene ring, followed by a concomitant disruption of the initially formed oxetane moiety and an aromatic ring of naphthalene moiety, can be regarded as a novel aromatic Paterno-Buechi reaction.