1450821-37-0

Basic information

• Product Name: (9aS,E)-8-ethylidene-3-methoxy-1-phenyl-7,8,9,9a-tetrahydro-1H-2-oxa-6a,10adiazabenzo[cd]cyclopenta[g]azulene-6,10-dione
• Synonyms: (9aS,E)-8-ethylidene-3-methoxy-1-phenyl-7,8,9,9a-tetrahydro-1H-2-oxa-6a,10adiazabenzo[cd]cyclopenta[g]azulene-6,10-dione
• CAS NO: 1450821-37-0
• Molecular Weight: 376.412
• Mol File: 1450821-37-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (9aS,E)-8-ethylidene-3-methoxy-1-phenyl-7,8,9,9a-tetrahydro-1H-2-oxa-6a,10adiazabenzo[cd]cyclopenta[g]azulene-6,10-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (9aS,E)-8-ethylidene-3-methoxy-1-phenyl-7,8,9,9a-tetrahydro-1H-2-oxa-6a,10adiazabenzo[cd]cyclopenta[g]azulene-6,10-dione(1450821-37-0)
• EPA Substance Registry System: (9aS,E)-8-ethylidene-3-methoxy-1-phenyl-7,8,9,9a-tetrahydro-1H-2-oxa-6a,10adiazabenzo[cd]cyclopenta[g]azulene-6,10-dione(1450821-37-0)

Safety Data

• Hazardous Substances Data: 1450821-37-0(Hazardous Substances Data)

Upstream product

• 1450821-30-3 (S)-2-((3-hydroxy-2-methylenebutyl)(4-methoxybenzyl)amino)acetic acid 2,2,2-trifluoroacetic acid salt 
• 736158-13-7 (2S)-3-(bromomethyl)but-3-en-2-ol 
• 1450821-34-7 (S,E)-methyl 4-ethylidenepyrrolidine-2-carboxylate hydrochloride 
• 1450821-28-9 (S)-tert-butyl 2-((3-hydroxy-2-methylenebutyl) (4-methoxybenzyl)amino)acetate 
• 90610-49-4 2-amino-3-hydroxy-4-methoxybenzoic acid methyl ester 
• 90564-40-2 methyl 3-hydroxy-4-methoxy-2-nitrobenzoate 
• 1450821-31-4 (S)-4-(4-methoxybenzyl)-7-methyl-6-methylene-1,4-oxazepan-2-one 
• 90222-57-4 2-amino-3-hydroxy-4-methoxybenzoic acid 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 1450821-36-9 (S,E)-2-ethylidene-9-hydroxy-8-methoxy-2,3-dihydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-5,11(10H,11aH)-dione 
• 1450821-32-5 (S,E)-methyl 4-ethylidene-1-(4-methoxybenzyl)pyrrolidine-2-carboxylate 
• 3206-46-0 5-(ethylsulfonyl)-1-phenyl-1H-tetrazole 
• 92964-20-0 methyl 3-(benzyloxy)-4-methoxy-2-nitrobenzoate 
• 92554-37-5 3-(benzyloxy)-4-methoxy-2-nitrobenzoic acid 

Relevant articles and documents

Modified Julia-Kocienski Reagents for a Stereoselective Introduction of Trisubstituted Double Bonds: A Formal Total Synthesis of Limazepine e and Barmumycin

A formal total synthesis of pyrrolo[1,4]benzodiazepine anticancer antibiotic family member limazepine E is described. The synthesis features a stereoselective introduction of a trisubstituted double bond using novel sterically demanding Julia-Kocienski re

The exocyclic olefin geometry control via Ireland-Claisen rearrangement: Stereoselective total syntheses of Barmumycin and Limazepine e

Stereoselective total syntheses of Limazepine E and Barmumycin, potent, naturally occurring antitumor agents, are described. The total syntheses control the olefin geometry via a highly selective chelation-controlled Ireland-Claisen rearrangement of a seven-membered lactone-derived boron enolate for the synthesis of (E)-4-ethylidene proline, a crucial building block for a number of natural products.