3206-46-0

Basic information

• Product Name: 1H-Tetrazole, 5-(ethylsulfonyl)-1-phenyl-
• Synonyms: 1H-Tetrazole, 5-(ethylsulfonyl)-1-phenyl-;5-(ethylsulfonyl)-1-phenyl-1H-tetraazole
• CAS NO: 3206-46-0
• Molecular Formula: C₉H₁₀N₄O₂S
• Molecular Weight: 238.2663
• Mol File: 3206-46-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 73-74 °C
• Boiling Point: 435.3±28.0 °C(Predicted)
• Appearance: /
• Density: 1.44±0.1 g/cm3(Predicted)
• PKA: -0.83±0.10(Predicted)
• CAS DataBase Reference: 1H-Tetrazole, 5-(ethylsulfonyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Tetrazole, 5-(ethylsulfonyl)-1-phenyl-(3206-46-0)
• EPA Substance Registry System: 1H-Tetrazole, 5-(ethylsulfonyl)-1-phenyl-(3206-46-0)

Safety Data

• Hazardous Substances Data: 3206-46-0(Hazardous Substances Data)

Usage

Structure

Tetrazole derivative containing both ethylsulfonyl and phenyl groups

Uses

Organic synthesis and pharmaceutical research, particularly in the development of new drugs and pharmaceuticals

Biological activities

Possesses potential biological activities and has been studied for its potential therapeutic properties

Research interest

Unique structure and properties make it an interesting target for further research and development in the field of medicinal chemistry and drug discovery

Upstream product

• 75-03-6 ethyl iodide 
• 86-93-1 1-Phenyl-1H-tetrazole-5-thiol 
• 74-96-4 ethyl bromide 
• 3206-45-9 5-ethylsulfanyl-1-phenyl-1H-tetrazole 

Downstream Products

• 1745-16-0 (E)-3-pentenylbenzene 
• 16487-65-3 (Z)-1-phenyl-3-pentene 
• 33398-23-1 C₁₂H₁₆O 
• 1353948-72-7 (E)-1,3-dichloro-2-(prop-1-en-1-yl)benzene 
• 1450821-37-0 (9aS,E)-8-ethylidene-3-methoxy-1-phenyl-7,8,9,9a-tetrahydro-1H-2-oxa-6a,10adiazabenzo[cd]cyclopenta[g]azulene-6,10-dione 
• 1352966-45-0 (2S,6S)-1-benzyl-2-methyl-6-((E)-prop-1-enyl)piperidine 

Relevant articles and documents

Total Synthesis and Bioactivity Studies of Fungal Metabolite (-)-TAN-2483B

The first total synthesis of (-)-TAN-2483B, a fungal metabolite possessing a densely functionalized furo[3,4-b]pyran-5-one framework, is achieved in 14 steps from d-mannose. Generation of the 2,6-trans-pyran is by cyclopropane ring expansion followed by α-selective alkynylation. Julia-Kocienski olefination introduces the E-propenyl side chain. Alkyne functionalization and carbonylation stereoselectively establish the bicyclic core of (-)-TAN-2483B. Inhibition of kinases Btk and Bmx, bacterial priority pathogens, and cytokine production in splenocytes indicates promising therapeutic potential.

SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES

The present invention relates to a pharmaceutical composition for treating or preventing CNS disorders containing a sulfamate derivative compound and/or pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or prevention CNS disorders comprising administering a sulfamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or prevention of CNS disorders.

Synthesis and chemical properties of 5-alkylsulfonyl-1-(4-nitrophenyl) tetrazoles

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