145593-32-4Relevant articles and documents
A SIMPLE AND CONVENIENT SYNTHESIS OF 2-PHOSPHONOMETHYL PYRIDINES
Page, Patrick,Mazieres, Marie-Rose,Bellan, Jacques,Sanchez, Michel
, p. 205 - 210 (2007/10/02)
The Michaelis-Becker-Nylen reaction is well suited for the synthesis of 2-phosphonomethyl pyridines.We have improved this four steps method in a one pot reaction using commercial reagents.By this general procedure we have prepared seven new 2-phosphonomethyl pyridines (Ia-g) under mild conditions with higher yields.Key words: 2-phosphono pyridines; 2-phosphonomethyl pyridines; Michaelis-Becker-Nylen reaction; new phosphonates; potential ligands.