14564-74-0

Basic information

• Product Name: potassium 4-dodecylbenzenesulphonate
• Synonyms: potassium 4-dodecylbenzenesulphonate;Benzenesulfonic acid, 4-dodecyl-, potassium salt;4-Dodecylbenzenesulfonic acid potassium salt;Benzenesulfonic acid, 4-dodecyl-, potassium salt (1:1);Einecs 238-608-5;Potassium p-dodecylbenzene sulfonate;potassium:4-dodecylbenzenesulfonate
• CAS NO: 14564-74-0
• Molecular Formula: C₁₈H₂₉O₃S*K
• Molecular Weight: 364.58436
• EINECS: 238-608-5
• Product Categories: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 14564-74-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• Storage Temp.: -20°C Freezer
• Solubility: Methanol (Very Slightly, Heated), Water (Slightly)
• CAS DataBase Reference: potassium 4-dodecylbenzenesulphonate(CAS DataBase Reference)
• NIST Chemistry Reference: potassium 4-dodecylbenzenesulphonate(14564-74-0)
• EPA Substance Registry System: potassium 4-dodecylbenzenesulphonate(14564-74-0)

Safety Data

• Hazardous Substances Data: 14564-74-0(Hazardous Substances Data)

Usage

Description

Potassium 4-dodecylbenzenesulphonate, also known as 4-dodecylbenzenesulfonic acid, is a synthetic organic compound with a unique structure that features a dodecyl chain attached to a benzene ring with a sulfonate group. It is a surfactant with both hydrophilic and hydrophobic properties, which allows it to interact with various substances and form micelles in aqueous solutions.

Uses

Used in Pharmaceutical Industry:
Potassium 4-dodecylbenzenesulphonate is used as a small-molecule inhibitor for targeting the pleckstrin homology domain of protein kinase B/AKT. This application is significant in the development of therapeutic strategies against various diseases, including cancer, where the AKT pathway plays a crucial role in cell survival and proliferation.
Used in Chemical and Material Science:
Due to its surfactant properties, potassium 4-dodecylbenzenesulphonate can be used as an additive in the chemical and material science industries. It can improve the solubility of hydrophobic compounds in aqueous solutions, enhance the stability of emulsions, and facilitate the formation of micelles for various applications, such as drug delivery and cleaning agents.
Used in Research and Development:
In the field of research and development, potassium 4-dodecylbenzenesulphonate can be employed as a tool compound to study the interactions between biological molecules and surfactants. It can also be used to investigate the effects of surfactants on the structure and function of proteins, membranes, and other biological systems.

InChI:InChI=1/C18H30O3S.K/c1-2-3-4-5-6-7-8-9-10-11-12-17-13-15-18(16-14-17)22(19,20)21;/h13-16H,2-12H2,1H3,(H,19,20,21);/q;+1/p-1

Upstream product

• 123-01-3 1-dodecylbenzene 

Downstream Products

• 52499-14-6 p-dodecylbenzenesulfonyl chloride 
• 1191951-85-5 4-dodecyl-N-(5-(5-(methyl(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)pentyl)-1,3,4-thiadiazol-2-yl)benzenesulfonamide 
• 1178893-79-2 N-(5-(5-bromopentyl)-1,3,4-thiadiazol-2-yl)-4-dodecylbenzenesulfonamide 
• 1191951-93-5 4-dodecyl-N-(5-(5-(methylamino)pentyl)-1,3,4-thiadiazol-2-yl)benzenesulfonamide 
• 1271729-65-7 N-(5-(5-chloropentyl)-1,3,4-thiadiazol-2-yl)-4-dodecyl benzenesulfonamide 
• 1191951-62-8 ethyl 2-(5-(4-dodecylphenylsulfonamido)-1,3,4-thiadiazol-2-yl)acetate 
• 1191951-61-7 2-(5-(4-dodecylphenylsulfonamido)-1,3,4-thiadiazol-2-yl)acetic acid 
• 1191951-63-9 ethyl 5-(4-dodecylphenylsulfonamido)-1,3,4-thiadiazole-2-carboxylate 
• 1191951-78-6 5-(4-dodecylphenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide 
• 1191951-64-0 4-dodecyl-N-(5-(hydroxymethyl)-1,3,4-thiadiazol-2-yl)benzenesulfonamide 
• 1191951-60-6 N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-4-dodecylbenzenesulfonamide 
• 1191951-59-3 4-dodecyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide 
• 1191951-58-2 4-dodecyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide 
• 1191951-57-1 ARC-183 

Relevant articles and documents

SMALL MOLECULE INHIBITORS OF THE PLECKSTRIN HOMOLOGY DOMAIN AND METHODS FOR USING SAME

Pleckstrin homology domain binding compounds, pharmaceutical compositions including such compounds, and methods for their use are described herein.