146388-52-5

Basic information

• Product Name: (2S,3R,4R)-(+)-3,4-epoxy-4-phenyl-2-butanol
• Synonyms: (2S,3R,4R)-(+)-3,4-epoxy-4-phenyl-2-butanol
• CAS NO: 146388-52-5
• Molecular Weight: 164.204
• Mol File: 146388-52-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (2S,3R,4R)-(+)-3,4-epoxy-4-phenyl-2-butanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,4R)-(+)-3,4-epoxy-4-phenyl-2-butanol(146388-52-5)
• EPA Substance Registry System: (2S,3R,4R)-(+)-3,4-epoxy-4-phenyl-2-butanol(146388-52-5)

Safety Data

• Hazardous Substances Data: 146388-52-5(Hazardous Substances Data)

Upstream product

• 146388-50-3 (3S,4R)-3,4-epoxy-4-phenylbutan-2-one 
• 104974-60-9 rac-(Z)-4-phenylbut-3-en-2-ol 
• 6249-79-2 trans-2-acetyl-3-phenyloxirane 
• 36004-04-3 ethyl (E)-1-phenylbut-1-en-3-ol 
• 73922-81-3 4-phenyl-but-3-yn-2-ol 
• 1896-62-4 (E)-benzalacetone 

Downstream Products

• 32426-79-2 1-((prop-1-enyloxy)methyl)benzene 
• 32426-80-5 (Z)-((prop-1-en-1-yloxy)methyl)benzene 
• 26164-26-1 (S)-2-methoxy-2-phenylacetic acid 
• 121618-63-1 tert-Butyl-dimethyl-[1-((2R,3S)-3-phenyl-oxiranyl)-ethoxy]-silane 
• 55775-43-4 2-Chloro-3,4-epoxy-4-phenylbutane 
• 110379-57-2 (S)-((S)-5-Methyl-[1,3]dioxolan-4-yl)-phenyl-methanol 
• 146388-54-7 (2S,3R,4S)-(+)-4-methoxy-4-phenyl-2,3-butanediol 

Relevant articles and documents

Stereodivergent Access to Enantioenriched Epoxy Alcohols with Three Stereogenic Centers via Ruthenium-Catalyzed Transfer Hydrogenation

The resolution technique of stereodivergent reaction on racemic mixtures (stereodivergent RRM) was employed for the first time in ruthenium complex catalyzed transfer hydrogenation of racemic epoxy ketones, providing a new and very simple method that allows access to enantioenriched epoxy alcohols with three stereogenic centers in a one-step fashion. The protocol features simple reaction conditions, practical operation, ability to scale up, and broad group tolerance.

Mechanistic implications of pseudo zero order kinetics in kinetic resolutions

This work provides simulations as well as experimental results from kinetic resolutions to demonstrate that a constant product enantioselectivity versus conversion profile in kinetic resolution is not a general consequence of pseudo zero order kinetics in

Synthesis of chiral epoxy alcohols by use of baker's yeast

Synthesis of optically active 3,4-epoxy-4-phenyl-2-butanols, which are expected to be useful intermediates for the synthesis of biologically active compounds such as β-blocker, was achieved by asymmetric reduction of 3,4-epoxy-4-phenyl-2-butanone with baker's yeast.