147082-33-5

Basic information

• Product Name: (4R,5S,6S)-3-[(3S,5S)-5-((S)-3-Dimethylamino-pyrrolidine-1-carbonyl)-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-3-ylsulfanyl]-6-((R)-1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester
• CAS NO: 147082-33-5
• Molecular Weight: 766.829
• Mol File: 147082-33-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4R,5S,6S)-3-[(3S,5S)-5-((S)-3-Dimethylamino-pyrrolidine-1-carbonyl)-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-3-ylsulfanyl]-6-((R)-1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S,6S)-3-[(3S,5S)-5-((S)-3-Dimethylamino-pyrrolidine-1-carbonyl)-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-3-ylsulfanyl]-6-((R)-1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester(147082-33-5)
• EPA Substance Registry System: (4R,5S,6S)-3-[(3S,5S)-5-((S)-3-Dimethylamino-pyrrolidine-1-carbonyl)-1-(4-nitro-benzyloxycarbonyl)-pyrrolidin-3-ylsulfanyl]-6-((R)-1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester(147082-33-5)

Safety Data

• Hazardous Substances Data: 147082-33-5(Hazardous Substances Data)

Upstream product

• 147082-06-2 (2S,4S)-4-(4-methoxybenzylthio)-1-(4-nitrobenzyloxycarbonyl)-2-pyrrolidinecarboxylic acid 
• 104873-15-6 4-nitrobenzyl (4R,5R,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3,7-dioxo-1-azabicyclo[3.2.0]-heptane-2-carboxylate 
• 147081-48-9 (2S,4S)-2-[(3S)-3-dimethylamino-1-pyrrolidinylcarbonyl]-4-(4-methoxybenzylthio)-1-(4-nitrobenzyloxycarbonyl)pyrrolidine 
• 93711-81-0 (4-nitrophenyl)methyl (4R,5R,6S)-3-[(diphenoxyphosphinyl)oxy]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 147558-26-7 (2S,4S)-2-((S)-3-Dimethylamino-pyrrolidine-1-carbonyl)-4-mercapto-pyrrolidine-1-carboxylic acid 4-nitro-benzyl ester 

Relevant articles and documents

Synthesis and antibacterial activity of novel 1 β-methyl carbapenems with cycloalkylamine moiety at the C-2 position

Novel 1β-methyl carbapenems with a cycloalkylamine moiety as a side chain were synthesized and their structure-activity relationships were studied. These carbapenems showed potent antibacterial activities against a wide range of range of Gram-positive and Gram-negative bacteria, and moderate urinary recovery when administered intraperitoneally in mice.