147225-13-6Relevant articles and documents
SYNTHESIS AND SRN1 REACTION OF THE FIRST QUINONE-OXAZOLE BIOREDUCTIVE ALKYLATING AGENT
Crozet, Michel P.,Sabuco, Jean-Francois,Tamburlin, Isabelle,Barreau, Michel,Giraud, Luc,Vanelle, Patrice
, p. 45 - 54 (2007/10/02)
2-(2-Chloromethyloxazol-5-yl)-3,5,6-trimethyl-1,4-benzoquinone, the first compound of a new quinone-heterocyclic class of bioreductive alkylating agent, was prepared from trimethylhydroquinone in 8 steps and reacted by SRN1 reaction with lithiu