147807-60-1Relevant articles and documents
Synthesis and in vitro leishmanicidal activity of some hydrazides and their analogues
Khan, Khalid Mohammad,Rasheed, Maimona,Ullah, Zia,Hayat, Safdar,Kaukab, Farhana,Choudhary, M. Iqbal,Ur-Rahman, Atta,Perveen, Shahnaz
, p. 1381 - 1387 (2007/10/03)
Twenty-one hydrazides were synthesized by treating different esters with hydrazine hydrate. Substituted hydrazides were obtained by treating hydrazides with alkyl/aryl/acyl halides. Some of these compounds exhibit potential in vitro leishmanicidal activity. The structures of all the synthesized compounds were confirmed by spectroscopic analysis.
Beta-N-cyanoethyl acyl hydrazide derivatives: a new class of beta-glucuronidase inhibitors.
Khan, Khalid Mohammed,Shujaat, Shahida,Rahat, Shagufta,Hayat, Safdar,Atta-ur-Rahman,Choudhary, Muhammad Iqbal
, p. 1443 - 1446 (2007/10/03)
Eight new beta-N-substituted acyl hydrazides along with their corresponding acyl derivatives were synthesized and screened for in vitro beta-glucuronidase inhibition and found to be active against the enzyme. All of these compounds were found to be noncom
Aryl substituted tetrazole derivatives, and application thereof in therapeutics
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, (2008/06/13)
Compounds for therapeutic use of formula: STR1 where the chain--W--V--N--represents--N=N--N--, --N--N=N--, --O--CO--N--, --O--CS--N--, --S--CO--N-- or --S--CS--N--; Ar is an aryl group; and A is a vinyl group or an alkylene chain terminated by CN, methoxy