148459-01-2Relevant articles and documents
1,2,4-oxadiazol derivatives compound and antiviral agent containing the same as an active ingredient
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Paragraph 0187; 0190-0193; 0247; 0250; 0255-0257, (2021/08/24)
1, 2, 4 - Oxadiazole derivative compounds and antiviral agents containing the same as an active ingredient. The compound has antiviral activity without cytotoxicity and has antiviral activity, and thus can be useful as an antiviral agent.
Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
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, (2008/06/13)
The present invention is directed to substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs thereof, represented by the Formula I: wherein Ar1, Ar3, A, B and D are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.