1486487-87-9

Basic information

• Product Name: 5-cyano-5-ethoxyformacyl-2-methyl-4-(3,4,5-trimethoxyphenyl)-4,5-dihydrooxazole
• Synonyms: 5-cyano-5-ethoxyformacyl-2-methyl-4-(3,4,5-trimethoxyphenyl)-4,5-dihydrooxazole
• CAS NO: 1486487-87-9
• Molecular Weight: 348.356
• Mol File: 1486487-87-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-cyano-5-ethoxyformacyl-2-methyl-4-(3,4,5-trimethoxyphenyl)-4,5-dihydrooxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-cyano-5-ethoxyformacyl-2-methyl-4-(3,4,5-trimethoxyphenyl)-4,5-dihydrooxazole(1486487-87-9)
• EPA Substance Registry System: 5-cyano-5-ethoxyformacyl-2-methyl-4-(3,4,5-trimethoxyphenyl)-4,5-dihydrooxazole(1486487-87-9)

Safety Data

• Hazardous Substances Data: 1486487-87-9(Hazardous Substances Data)

Upstream product

• 2601-03-8 2-cyano-3-(3,4,5-trimethoxyphenyl)acrylic acid ethyl ester 
• 79-15-2 N-bromoacetamide 

Relevant articles and documents

One-pot synthesis of 2-oxazolines from ethyl α-cyanocinnamate derivatives with n-bromoacetamide

An efficient method for the one-pot synthesis of 2-oxazolines from ethyl α-cyanocinnamate derivatives with N-bromoacetamide in the presence of K3PO4 has been developed. The reaction performed smoothly and cleanly to give 2-oxazolines in good to excellent yields (up to 98%) within 4.5 h in acetone at room temperature without protection of inert gases. A total of 13 examples have been investigated. A possible nucleophilic addition reaction mechanism is proposed.