148774-47-4 Usage
Description
Δ2-Cefditoren Pivoxil is a metabolite of Cefditoren Pivoxil, which is an antibacterial agent belonging to the third generation of cephalosporins. It is derived from the parent compound through metabolic processes in the body and exhibits potent antimicrobial properties.
Uses
Used in Pharmaceutical Industry:
Δ2-Cefditoren Pivoxil is used as an antibacterial agent for the treatment of various bacterial infections. Its application is particularly relevant due to its effectiveness against a wide range of bacterial pathogens, including those resistant to other cephalosporins. The metabolite's role in enhancing the efficacy and broadening the spectrum of the parent drug makes it a valuable component in the fight against antibiotic-resistant infections.
Check Digit Verification of cas no
The CAS Registry Mumber 148774-47-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,7,7 and 4 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 148774-47:
(8*1)+(7*4)+(6*8)+(5*7)+(4*7)+(3*4)+(2*4)+(1*7)=174
174 % 10 = 4
So 148774-47-4 is a valid CAS Registry Number.
148774-47-4Relevant articles and documents
Preparation methods of Cefditoren acid delta 3 isomer and cefditoren pivoxil delta 3 isomer
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Paragraph 0148-0175, (2019/11/12)
The invention discloses preparation methods of Cefditoren acid delta 3 isomer and cefditoren pivoxil delta 3 isomer. The cefditoren acid delta 3 isomer is prepared from the following steps that pure water and tetrahydrofuran are added in a reaction vessel, the temperature is lowered to 0-5 DEG C, a 7-ATCA delta 3 isomer and AE active ester (MAEM) are added, after adding is completed, then organicalkali is dropwise added to control pH of 8.0-8.5, the organic alkali is needed to be additionally added to keep the pH of 8.0-8.5, dichloromethane and water are added after reaction is completed, stirring and extraction are conducted, still standing and layering are conducted, a lower organic layer is discarded, the pH of an upper water layer is 3.0-3.5, stirring and filtering are conducted, andwashing and drying are conducted to obtain a product. The content of the cefditoren acid delta 3 isomer and the cefditoren pivoxil delta 3 isomer which are prepared through the preparation method canreach above 93%.
