148891-53-6Relevant articles and documents
Preparation method of dexzopiclone photodegradation impurity
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Paragraph 0017; 0019; 0021; 0023, (2020/12/30)
The invention relates to a preparation method of a dexzopiclone photodegradable impurity, and belongs to the technical field of chemical synthesis. The invention relates to a preparation method of 6-(5-chloropyridin-2-yl)-6, 7-dihydro-5H-pyrrolo [3, 4-b] pyrazin-5-one (compound I), which is prepared by reacting a compound II or a compound III with diisobutylaluminum hydride under certain conditions. The invention provides a synthetic method of the 6-(5-chloropyridin-2-yl)-6, 7-dihydro-5H-pyrrolo [3, 4-b] pyrazin-5-one (compound I), which is reasonable in process, mild in condition and simple and convenient to operate, and the method is simple to operate and has a certain commercial value.