149105-19-1 Usage
Description
2-Carboxyphenylboronic acid is an organic compound with the chemical formula C6H4(COOH)(B(OH)2). It is a white powder that possesses unique chemical properties, making it a versatile molecule for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
2-Carboxyphenylboronic acid is used as a key component in the development of a new class of carbohydrate-binding boronic acids called the boronophthalide. These sugar-binding boronic acids are soluble and capable of complexing glycosides in neutral water, which can be utilized in the design of drugs targeting specific carbohydrate recognition processes in biological systems.
Used in Chemical Research:
2-Carboxyphenylboronic acid serves as an essential reagent in chemical research, particularly in the synthesis of various organic compounds and the study of their properties. Its unique structure allows for the exploration of new chemical reactions and the development of novel synthetic pathways.
Used in Material Science:
In the field of material science, 2-Carboxyphenylboronic acid can be employed as a building block for the development of new materials with specific properties, such as optical, electronic, or mechanical characteristics. Its ability to form complexes with other molecules can be exploited to create advanced materials for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 149105-19-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,1,0 and 5 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 149105-19:
(8*1)+(7*4)+(6*9)+(5*1)+(4*0)+(3*5)+(2*1)+(1*9)=121
121 % 10 = 1
So 149105-19-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H7BO4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4,11-12H,(H,9,10)
149105-19-1Relevant articles and documents
A practical preparation of 2-carboxyphenylboronic acid and its application for the preparation of biaryl-2-carboxylic acids using Suzuki coupling reactions
Tao, Bin,Goel, Subhash C.,Singh, Jagvir,Boykin, David W.
, p. 1043 - 1046 (2002)
A practical synthesis of 2-carboxyphenylboronic from 2-tolylboronic acid and aqueous potassium permanganate under mild conditions is reported. The title compound couples with aryl bromides containing electron-withdrawing groups to give biaryl-2-carboxylic
METHOD FOR THE PRODUCTION OF BORONIC ACIDS CARRYING CYANOALKYL, CARBOXYL AND AMINOCARBONYL GROUPS AND THEIR DERIVATIVES
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Page/Page column 4, (2009/12/05)
A process for the manufacture of aminocarbonyl boronic acids of formula (IV) by converting the compounds of formula (III) with a Br?nsted base Y(OH)n in a solvent or a solvent mixture, in which Z represents an optionally substituted arylene, heteroarylene, alkene, heteroalkene, alkylidene, heteroalkylidene, alkenylidene, heteroalkenylidene, alkynylidene, arylalkylene, heteroarylalkylene, arylheteroalkylene, heteroarylheteroalkylene, alkylheteroarylene, heteroalkylheteroarylene, or alkylarylene group; Y represents a metal or ammonium cation of valence n with 0n5; and B represents boronic acid, boronic acid ester, or a borate, or a boronic acid anhydride. The aminocarbonyl boronic acids of formula (IV) can be further hydrolyzed to form the carboxy boronic acid of formula (V).