37174-74-6

Basic information

• Product Name: 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLIC ACID
• Synonyms: 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLIC ACID;AKOS BAR-1975;3'-NITRO-2-BIPHENYLCARBOXYLIC ACID;OTAVA-BB 1363645;2-(3-Nitrophenyl)benzoic acid;3'-Nitrobiphenyl-2-carboxylic acid
• CAS NO: 37174-74-6
• Molecular Formula: C13H9NO4
• Molecular Weight: 243.21
• Mol File: 37174-74-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLIC ACID(37174-74-6)
• EPA Substance Registry System: 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLIC ACID(37174-74-6)

Safety Data

• Hazardous Substances Data: 37174-74-6(Hazardous Substances Data)

Usage

General Description

3'-Nitro[1,1'-biphenyl]-2-carboxylic acid is a chemical compound with the molecular formula C13H9NO4. It is a derivative of biphenyl, a type of aromatic hydrocarbon, and contains a nitro group and a carboxylic acid group attached to the biphenyl core. 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLIC ACID is often used as a precursor in the synthesis of various pharmaceuticals, agrochemicals, and dyes. It may also have applications in organic synthesis and materials science. Its properties and reactivity make it a valuable building block for creating complex organic molecules with specific functionalities.

Upstream product

• 83527-96-2 methyl 3’-nitro-[1,1’-biphenyl]-2-carboxylate 
• 88-67-5 2-Iodobenzoic acid 
• 1829-28-3 ethyl 2-iodobenzoate 
• 1195761-05-7 ethyl 3'-nitrobiphenyl-2-carboxylate 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 13331-27-6 m-nitrobenzene boronic acid 
• 16278-29-8 3-nitrobenzenediazonium 
• 585-79-5 m-nitrobromobenzene 
• 149105-19-1 2-carboxyphenylboronic acid 
• 51264-60-9 3-nitro-2'-methylbiphenyl 
• 93-58-3 benzoic acid methyl ester 
• 16419-60-6 2-Methylphenylboronic acid 

Downstream Products

• 6623-66-1 6-nitro-3,4-benzocoumarin 
• 107916-96-1 2-carboxy-3'-cyanobiphenyl 
• 103167-29-9 bis-(3'-nitro-biphenyl-2-carbonyl)-peroxide 
• 83527-96-2 methyl 3’-nitro-[1,1’-biphenyl]-2-carboxylate 
• 67856-54-6 3'-amino-biphenyl-2-carboxylic acid 

Relevant articles and documents

Mechanochemical-Cascaded C-N Cross-Coupling and Halogenation Using N-Bromo- And N-Chlorosuccinimide as Bifunctional Reagents

Exploration of alternative energy sources for chemical transformations has gained significant interest from chemists, and mechanochemistry is one of those sources. Herein, we report the use of N-bromosuccinimides (NBS) and N-chlorosuccinimides (NCS) as bifunctional reagents for a cascaded C-N bond formation and subsequent halogenation reactions. Under the solvent-free mechanochemical (ball-milling) conditions, the synthesis of a wide range of phenanthridinone derivatives from N-methoxy-[1,1′-biphenyl]-2-carboxamides is accomplished. During the reactions, NBS and NCS first assisted the oxidative C-N coupling reaction and subsequently promoted a halogenation reaction. Thus, the role of NBS and NCS was established to be bifunctional. Overall, a mild, solvent-free, convenient, one-pot, and direct synthesis of various bromo- and chloro-substituted phenanthridinone derivatives was achieved.

General and practical carboxyl-group-directed remote C-H oxygenation reactions of arenes

Two methods for remote aromatic C-H oxygenation reactions, have been developed. Method1, the Cu-catalyzed oxygenation reaction, is highly efficient for cyclization of electron-neutral and electron-rich biaryl carboxylic acids into 3,4-benzocoumarins. Method2, the K2S2O 8-mediated oxygenation reaction, is more general and practical for cyclization of substrates with electron-donating and -withdrawing groups (see scheme). Copyright

SEMISYNTHETIC PENICILLINS. I. 2-BIPHENYLYLPENICILLINS.

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