83527-96-2

Basic information

• Product Name: METHYL 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLATE
• Synonyms: AKOS BAR-1976;METHYL 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLATE;Methyl 2-(3-nitrophenyl)benzoate
• CAS NO: 83527-96-2
• Molecular Formula: C14H11NO4
• Molecular Weight: 257.24
• Mol File: 83527-96-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: METHYL 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLATE(83527-96-2)
• EPA Substance Registry System: METHYL 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLATE(83527-96-2)

Safety Data

• Hazardous Substances Data: 83527-96-2(Hazardous Substances Data)

Usage

General Description

Methyl 3'-nitro[1,1'-biphenyl]-2-carboxylate is a chemical compound with the molecular formula C15H11NO4. It is an ester of nitro-substituted biphenyl carboxylic acid, and is commonly used in organic synthesis and medicinal chemistry. METHYL 3'-NITRO[1,1'-BIPHENYL]-2-CARBOXYLATE has potential applications in the development of pharmaceuticals and agrochemicals due to its unique molecular structure and reactivity. Additionally, it may also be used as an intermediate in the synthesis of various organic compounds. However, due to its nitro-substituted structure, it is important to handle and store this chemical with caution and follow proper safety protocols to prevent any potential hazards.

Upstream product

• 93-58-3 benzoic acid methyl ester 
• 16278-29-8 3-nitrobenzenediazonium 
• 37174-74-6 3'-nitro-[1,1'-biphenyl]-2-carboxylic acid 
• 98-95-3 nitrobenzene 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 13331-27-6 m-nitrobenzene boronic acid 
• 88-67-5 2-Iodobenzoic acid 
• 610-97-9 o-iodo-methyl-benzoic acid 

Downstream Products

• 6623-66-1 6-nitro-3,4-benzocoumarin 
• 103167-29-9 bis-(3'-nitro-biphenyl-2-carbonyl)-peroxide 
• 107916-96-1 2-carboxy-3'-cyanobiphenyl 
• 67856-54-6 3'-amino-biphenyl-2-carboxylic acid 
• 37174-74-6 3'-nitro-[1,1'-biphenyl]-2-carboxylic acid 

Relevant articles and documents

Mechanochemical-Cascaded C-N Cross-Coupling and Halogenation Using N-Bromo- And N-Chlorosuccinimide as Bifunctional Reagents

Exploration of alternative energy sources for chemical transformations has gained significant interest from chemists, and mechanochemistry is one of those sources. Herein, we report the use of N-bromosuccinimides (NBS) and N-chlorosuccinimides (NCS) as bifunctional reagents for a cascaded C-N bond formation and subsequent halogenation reactions. Under the solvent-free mechanochemical (ball-milling) conditions, the synthesis of a wide range of phenanthridinone derivatives from N-methoxy-[1,1′-biphenyl]-2-carboxamides is accomplished. During the reactions, NBS and NCS first assisted the oxidative C-N coupling reaction and subsequently promoted a halogenation reaction. Thus, the role of NBS and NCS was established to be bifunctional. Overall, a mild, solvent-free, convenient, one-pot, and direct synthesis of various bromo- and chloro-substituted phenanthridinone derivatives was achieved.

Pd nanoparticle-silica nanotubes (Pd@SNTs) as an efficient catalyst for Suzuki-Miyaura coupling and sp2 C-H arylation in water

Silica nanotubes (SNTs) functionalized with Pd-NPs on the inner surface performed as efficient nano-reactors for C-C coupling in water; the nano-confinement offers minimized leaching of Pd and yet efficient mass transfer for Suzuki-Miyaura coupling and C-H arylation of thiazoles in water with very high TON.

Biarylaniline phenethanolamines as potent and selective β3 adrenergic receptor agonists

The synthesis of a series of phenethanolamine aniline agonists that contain an aniline ring on the right-hand side of the molecule substituted at the meta position with a benzoic acid or a pyridyl carboxylate is described. Several of the analogues (e.g.,