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14925-10-1

14925-10-1

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14925-10-1 Usage

Chemical Properties

Colorless liquid

Uses

N-Methyl-2-(trifluoromethyl)aniline

Check Digit Verification of cas no

The CAS Registry Mumber 14925-10-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,9,2 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 14925-10:
(7*1)+(6*4)+(5*9)+(4*2)+(3*5)+(2*1)+(1*0)=101
101 % 10 = 1
So 14925-10-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H8F3N/c1-12-7-5-3-2-4-6(7)8(9,10)11/h2-5,12H,1H3

14925-10-1 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (L09801)  N-Methyl-2-(trifluoromethyl)aniline, 96%   

  • 14925-10-1

  • 1g

  • 487.0CNY

  • Detail

  • Alfa Aesar

  • (L09801)  N-Methyl-2-(trifluoromethyl)aniline, 96%   

  • 14925-10-1

  • 5g

  • 2015.0CNY

  • Detail

14925-10-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-Methyl-2-(trifluoromethyl)aniline

1.2 Other means of identification

Product number -
Other names N-methyl-2-(trifluoromethyl)aniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14925-10-1 SDS

14925-10-1Relevant articles and documents

Synthesis and muscarinic activity of novel aniline derivatives with a 1- azabicyclo[3.3.0]octane moiety

Suzuki, Tomoo,Oka, Mitsuru,Maeda, Kouji,Furusawa, Kenichi,Uesaka, Hiroshi,Kataoka, Tadashi

, p. 28 - 36 (2007/10/03)

In order to develop drugs effective against Alzheimer's disease, we synthesized a series of aniline derivatives having a characteristic cyclic amine, 1-azabicyclo[3.3.0]octane ring, and evaluated their binding affinity for the central muscarinic cholinergic receptor. Among these compounds which showed high affinity to the M1 receptor, N-[2-(1-Azabicyclo[3.3.0]octan-5- yl)ethyl]-2-nitroaniline (9f fumarate, SK-946) showed the highest affinity. The ability of this compound to improve cognitive function was assessed using the passive avoidance test in scopolamine-induced dementia mice. Some anilines with a 1-azabicyclo[3.3.1]nonane ring were also synthesized by the ring expansion of the 1-azabicyclo[3.3.0]octane ring, and showed a high affinity for the central muscarinic cholinergic receptor.

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