149777-85-5

Basic information

• Product Name: 4-forMyl-trans-beta-styrylboronic acid pinacol ester
• Synonyms: 4-forMyl-trans-beta-styrylboronic acid pinacol ester
• CAS NO: 149777-85-5
• Molecular Formula: C₁₅H₁₉BO₃
• Molecular Weight: 276
• Mol File: 149777-85-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-forMyl-trans-beta-styrylboronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-forMyl-trans-beta-styrylboronic acid pinacol ester(149777-85-5)
• EPA Substance Registry System: 4-forMyl-trans-beta-styrylboronic acid pinacol ester(149777-85-5)

Safety Data

• Hazardous Substances Data: 149777-85-5(Hazardous Substances Data)

Upstream product

• 63697-96-1 4-Ethynylbenzaldehyde 
• 73183-34-3 bis(pinacol)diborane 
• 1122-91-4 4-bromo-benzaldehyde 
• 75927-49-0 pinacol vinylboronate 

Downstream Products

• 1252060-56-2 2-(carbamoylamino)-5-[(E)-2-(4-formylphenyl)vinyl]thiophene-3-carboxamide 
• 1338806-73-7 (1R*,2S*)-(E)-(2-(3-(4-(cis-2,6-dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one 
• 933986-43-7 (E)-N-ethyl-N-(4-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)benzyl)ethananamine 
• 1160919-86-7 5-[(E)-2-(4-formylphenyl)ethenyl]-6-methyl-4-[(4-methyl-1H-indol-5-yl)amino]pyridine-3-carbonitrile 
• 1160918-55-7 5-[(E)-2-(4-formylphenyl)vinyl]-4-[(4-methyl-1H-indol-5-yl)amino]nicotinonitrile 

Relevant articles and documents

Electrochemical Hydroboration of Alkynes

Herein we reported the electrochemical hydroboration of alkynes by using B2Pin2 as the boron source. This unprecedented reaction manifold was applied to a broad range of alkynes, giving the hydroboration products in good to excellent yields without the need of a metal catalyst or a hydride source. This transformation relied on the possible electrochemical oxidation of an in situ formed borate. This anodic oxidation performed in an undivided cell allowed the formation of a putative boryl radical, which reacted on the alkyne.

FUSED THIOPHENE COMPOUNDS

The present disclosure provides compounds that modulate protein function of 1 L-1β, IL-2, IL-6, TNF-α, CK1α, GSPT1, aiolos, ikaros or helios, to restore protein homeostasis, and 1 cell-cell adhesion. The disclosure provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators are provided. Uses of compounds for treatment or amelioration of diseases, disorders, or conditions associated with a protein, are also provided.

THIOPHENE INHIBITORS OF IKK-B SERINE-THREONINE PROTEIN KINASE

The invention provides a compound which is (a) a thiophene carboxamide derivative of formula (IA) or (IB), or a tautomer thereof; or (b) a pharmaceutically acceptable salt, N-oxide, hydrate or solvate thereof, wherein L1, A1 and W ar