14983-92-7

Basic information

• Product Name: (2-Methylphenyl)carbamic acid methyl ester
• Synonyms: (2-Methylphenyl)carbamic acid methyl ester;N-(2-Methylphenyl)carbamic acid methyl ester;METHYL N-(O-TOLYL)CARBAMATE
• CAS NO: 14983-92-7
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.19
• Mol File: 14983-92-7.mol
• Article Data: 30

Chemical Properties

• Melting Point: 52-53 °C(Solv: dichloromethane (75-09-2); hexane (110-54-3))
• Boiling Point: 202.5±19.0 °C(Predicted)
• Appearance: /
• Density: 1.138±0.06 g/cm3(Predicted)
• PKA: 13.87±0.70(Predicted)
• CAS DataBase Reference: (2-Methylphenyl)carbamic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Methylphenyl)carbamic acid methyl ester(14983-92-7)
• EPA Substance Registry System: (2-Methylphenyl)carbamic acid methyl ester(14983-92-7)

Safety Data

• Hazardous Substances Data: 14983-92-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 113, p. 1054, 1991 DOI: 10.1021/ja00003a056

Upstream product

• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 88-72-2 1-methyl-2-nitrobenzene 
• 95-53-4 o-toluidine 
• 73708-95-9 methyl 3-oxo-2-oximinobutanoate 
• 124-38-9 carbon dioxide 
• 6294-89-9 hydrazinecarboxylic acid methyl ester 
• 79-22-1 methyl chloroformate 
• 616-38-6 carbonic acid dimethyl ester 
• 527-85-5 o-Methylbenzamid 
• 614-68-6 2-tolyl isocyanate 
• 2597-44-6 formyl radical 
• 31656-92-5 1-azido-2-methyl-benzene 
• 584-90-7 2,2'-dimethylazobenzene 

Downstream Products

• 95-69-2 4-chloro-2-methylbenzeneamine 
• 10541-29-4 2-methyl-N-methylaniline hydrochloride 
• 117550-42-2 methyl N-[2-(chloromethyl)phenyl]carbamate 
• 57735-51-0 Benzyloxycarbonyl-L-alanin-N-methyl-2-methylanilid 
• 63379-17-9 2-methylcarbamoyl-4-nitro-toluene 
• 924666-87-5 (2-methyl-5-nitroso-phenyl)-carbamic acid methyl ester 
• 611-21-2 N,2-dimethylaniline 
• 39074-42-5 Chloromethyl-o-tolyl-carbamic acid methyl ester 
• 151830-30-7 methyl N-ethyl-N-(o-methylphenyl)-carbamate 

Relevant articles and documents

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Copper-Catalyzed Coupling of Amines with Carbazates: An Approach to Carbamates

A new approach for the preparation of carbamatesviathe copper-catalyzed cross-coupling reaction of amines with alkoxycarbonyl radicals generated from carbazates is described. This environmentally friendly protocol takes place under mild conditions and is compatible with a wide range of amines, including aromatic/aliphatic and primary/secondary substrates.

Method for synthesizing P-chloroO-toluidine

The invention discloses a method for synthesizing p-chloroo-toluidine, which comprises the following steps: synthesizing o-toluidine and a protective agent in an organic solvent to obtain an amino-protected intermediate. The amino protected intermediate is added into hydrochloric acid, an oxidant is added for chlorination reaction, and a chlorination product is obtained. The chlorinated product is removed and the amino protecting group is removed to give p-chloroo-toluidine. The method for synthesizing p-chloroo-toluidine provided by the invention is high in yield, simple to operate, less in three wastes, high in product content and good in quality, and can be suitable for industrial mass production.

Preparation method of pyridine quinazoline intermediate (by machine translation)

The invention discloses a preparation method of a pyridine quinazoline intermediate, wherein: the 2 - preparation method of the, pyridine quinazoline intermediate comprises, the following steps, of: performing, substitution reaction and 3 - ring-forming r