150607-94-6 Usage
Description
Methyl 1,2,3,4-Tetra-O-isobutyryl-b-D-glucopyranuronate, with the CAS number 150607-94-6, is a pink solid compound that is useful in organic synthesis. It is a derivative of b-D-glucopyranuronate, a component of certain polysaccharides, with four isobutyryl groups attached to its hydroxyl groups.
Uses
Used in Organic Synthesis:
Methyl 1,2,3,4-Tetra-O-isobutyryl-b-D-glucopyranuronate is used as an intermediate in the synthesis of various organic compounds. Its unique structure and functional groups make it a valuable building block for creating complex molecules with specific properties and applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methyl 1,2,3,4-Tetra-O-isobutyryl-b-D-glucopyranuronate may be used as a starting material for the development of new drugs, particularly those targeting specific biological pathways or receptors. Its structural features can be exploited to design molecules with enhanced bioactivity and selectivity.
Used in Chemical Research:
Methyl 1,2,3,4-Tetra-O-isobutyryl-b-D-glucopyranuronate is also used in chemical research to study the properties and reactivity of isobutyryl-protected glucopyranuronate derivatives. This can lead to a better understanding of the underlying chemistry and the development of new synthetic strategies and methodologies.
Used in Material Science:
In material science, Methyl 1,2,3,4-Tetra-O-isobutyryl-b-D-glucopyranuronate could potentially be used to develop new materials with specific properties, such as improved mechanical strength, thermal stability, or biocompatibility. Its unique structure and functional groups can be utilized to create novel polymers or composites with tailored characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 150607-94-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,6,0 and 7 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 150607-94:
(8*1)+(7*5)+(6*0)+(5*6)+(4*0)+(3*7)+(2*9)+(1*4)=116
116 % 10 = 6
So 150607-94-6 is a valid CAS Registry Number.
150607-94-6Relevant articles and documents
A convenient new synthesis of quaternary ammonium glucuronides of drug molecules
Iddon, Lisa,Bragg, Ryan A.,Harding, John R.,Stachulski, Andrew V.
scheme or table, p. 537 - 541 (2010/03/03)
N-Glucuronides, of various structural types, are frequently encountered as drug metabolites. Efficient chemical synthesis of these compounds, both as analytical standards and for toxicological investigation, is therefore an important goal. Earlier syntheses of N+- glucuronides of aliphatic tertiary amine drugs involved direct reaction of the drug molecule with a bromosugar, but yields were generally low and of poor reproducibility, with many by-products. In addition the final products were often of low stability, hindering effective isolation and purification. We now report that a stable, readily prepared glucuronic acid hemiacetal is a reliable precursor for metabolites of this type and give three pharmaceutically relevant examples. We report further on the stability of the final metabolites and the conditions required for their isolation and purification.
Convenient syntheses of deoxypyranose sugars from glucuronolactone
Stanford (nee Sinnott), Deborah,Stachulski, Andrew V.
, p. 2361 - 2364 (2007/10/03)
One of the characteristic reactions of glucuronic acid derivatives is the base-catalysed elimination of a 4-(substituted) hydroxy group to generate a Δ4,5 pyranose. Following hydrogenation, proceeding mainly from the α-face provided the anomeri
Synthesis of a Morphine-6-Glucuronide Hapten, N-(4-Aminobutyl)normorphine-6-Glucuronide, and Related Haptens
Brown, Richard T.,Carter, Neil E.,Lumbard, Keith W.,Scheinmann, Feodor
, p. 8661 - 8664 (2007/10/02)
For use as a hapten in the radioimmunoassay of morphine-6-glucuronide (2) (M6G), N-(4-aminobutyl)normorphine-6-glucuronide 12 has been prepared, together with related haptens, using the imidate coupling method developed for synthesis of M6G; a rebuttal of recent critical comments on our synthesis of M6G is included.
