487-44-5Relevant articles and documents
Chemical structures of constituents from the leaves of Polyscias balfouriana
Sugimoto, Sachiko,Yamano, Yoshi,Khalil, Hany Ezzat,Otsuka, Hideaki,Kamel, Mohamed Salah,Matsunami, Katsuyoshi
, p. 558 - 563 (2017)
A new pyrrolidine derivative, (5S)-hydroxyethyl 2-oxopyrrolidine-5-carboxylate (1), a new flavonol glycoside, tamaraxetin 3,7-di-O-α-l-rhamnopyranoside (2), and a new triterpene saponin, polyscioside A methyl ester (3), along with six known compounds (4–9) were isolated from the leaves of Polyscias balfouriana. Their chemical structures were elucidated on the basis of extensive spectroscopic analysis.
Design and synthesis by click triazole formation of paclitaxel mimics with simplified core and side-chain structures
Manach, Claire Le,Baron, Aurélie,Guillot, Régis,Vauzeilles, Boris,Beau, Jean-Marie
scheme or table, p. 1462 - 1465 (2011/06/10)
A library of paclitaxel (taxol) mimics was obtained by a straightforward strategy involving rational design and an efficient synthesis of a simplified taxane core substitute, together with a click-chemistry combinatorial search for phenylisoserine side-chain surrogates.
Degradation kinetics of glucuronic acid in subcritical water
Wang, Rongchun,Neoh, Tze Loon,Kobayashi, Takashi,Miyake, Yasuhito,Hosoda, Asao,Taniguchi, Hisaji,Adachi, Shuji
experimental part, p. 601 - 605 (2011/04/23)
The degradation kinetics of glucuronic acid (GlcA) under subcritical conditions from 160 to 200 °C was studied in a continuous tubular reactor. The formation of glucuronolactone (GlcL) during the treatment of GlcA in subcritical water was substantiated by ESITOF-MS and 1H NMR. The degradation of GlcA consisted of the reversible conversion of GlcA to GlcL and the irreversible degradation of the two compounds. The changes in the concentrations of GlcA and GlcL with residence time could be described by first-order kinetics. Higher temperatures accelerated the degradation of GlcA, and thus resulted in rises in the pH value. The degradation reaction of GlcL under the same conditions was also investigated. The activation energy of the reverse hydrolysis of GlcA to GlcL and that of the hydrolysis of GlcL to GlcA were determined to be 88.5 and 63.2 kJ/mol respectively. The enthalpy change in the reversible conversion between GlcA and GlcL was 25.4 kJ/mol.