150932-53-9

Basic information

• Product Name: (E)-(3R,4R)-6-((3aR,7aR)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-4-methyl-3-phenyl-hex-5-enoic acid tert-butyl ester
• Synonyms: (E)-(3R,4R)-6-((3aR,7aR)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-4-methyl-3-phenyl-hex-5-enoic acid tert-butyl ester
• CAS NO: 150932-53-9
• Molecular Weight: 446.57
• Mol File: 150932-53-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-(3R,4R)-6-((3aR,7aR)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-4-methyl-3-phenyl-hex-5-enoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(3R,4R)-6-((3aR,7aR)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-4-methyl-3-phenyl-hex-5-enoic acid tert-butyl ester(150932-53-9)
• EPA Substance Registry System: (E)-(3R,4R)-6-((3aR,7aR)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-4-methyl-3-phenyl-hex-5-enoic acid tert-butyl ester(150932-53-9)

Safety Data

• Hazardous Substances Data: 150932-53-9(Hazardous Substances Data)

Upstream product

• 14990-09-1 tert-butyl cinnamate 
• 150932-41-5 (3aR,7aR)-2-crotyloctahydro-1H-1,3-dimethyl-1,3,2-benzadiazaphosphole 2-oxide 
• 68737-65-5 (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane 

Downstream Products

• 150932-71-1 (3R,4R)-5-Hydroxy-4-methyl-3-phenyl-pentanoic acid tert-butyl ester 

Relevant articles and documents

Asymmetric conjugate additions of chiral phosphonamide anions to α,β-unsaturated carbonyl compounds. A versatile method for vicinally substituted chirons

Reactions of anions derived from chiral nonracemic allyl, crotyl, and cinnamyl bicyclic C2-symmetrical phosphonamides with α,β-unsaturated cyclic ketones, esters, lactones, and lactams take place at the γ-position of the reagents. The products are diastereomerically pure or enriched β-substituted carbonyl compounds. The method also provides easy access to vicinal substitution of as many as three stereogenic centers including in some cases quaternary carbon atoms, in a one-pot sequence.