151121-12-9Relevant articles and documents
BF3·OEt2-promoted diastereoselective diacetoxylation of alkenes by PhI(OAc)2
Zhong, Wenhe,Yang, Jun,Meng, Xiangbao,Li, Zhongjun
, p. 9997 - 10004 (2011)
Selective syn and anti diacetoxylations of alkenes have been achieved using a PhI(OAc)2/BF3·OEt2 system in the presence and absence of water, respectively. A broad range of substrates including electron-deficient alkenes (such as α,β-unsaturated esters) could be elaborated efficiently at room temperature with this methodology, furnishing the desired products in good to excellent yields and diastereoselectivity. In particular, a multigram-scale diastereoselective diacetoxylation of methyl cinnamate (5.00 g) was also accomplished in a few hours, maintaining the same efficiency as small-scale reaction. This novel methodology provides an alternative approach for the preparation of various 1,2-diols.
Aerobic palladium-catalyzed dioxygenation of alkenes enabled by catalytic nitrite
Wickens, Zachary K.,Guzmn, Pablo E.,Grubbs, Robert H.
supporting information, p. 236 - 240 (2015/02/05)
Catalytic nitrite was found to enable carbon-oxygen bond-forming reductive elimination from unstable alkyl palladium intermediates, providing dioxygenated products from alkenes. Avariety of functional groups were tolerated, and high yields (up to 94%) were observed with many substrates, also for a multigram-scale reaction. Nitrogen dioxide, which could form from nitrite under the reaction conditions, was demonstrated to be a potential intermediate in the catalytic cycle. Furthermore, the reductive elimination event was probed with 18O-labeling experiments, which demonstrated that both oxygen atoms in the difunctionalized products were derived from one molecule of acetic acid.
Lipid-improving agent and composition containing lipid-improving agent
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Page/Page column 7, (2010/11/23)
A lipid-improving agent containing a triglyceride(s) where a poly-unsaturated fatty acid is bonded to 2-position of a triglyceride(s).
