4152-39-0

Basic information

• Product Name: 1-O-acetyl-3-O-benzylpropane-1,2,3-triol
• Synonyms: 1-O-acetyl-3-O-benzylpropane-1,2,3-triol
• CAS NO: 4152-39-0
• Molecular Weight: 224.257
• Mol File: 4152-39-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-O-acetyl-3-O-benzylpropane-1,2,3-triol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O-acetyl-3-O-benzylpropane-1,2,3-triol(4152-39-0)
• EPA Substance Registry System: 1-O-acetyl-3-O-benzylpropane-1,2,3-triol(4152-39-0)

Safety Data

• Hazardous Substances Data: 4152-39-0(Hazardous Substances Data)

Usage

Source

Derived from the natural resin called taxadiene.

Molecular structure

Composed of a triol structure with a benzyl and acetyl group attached to carbon atoms.

Pharmaceutical applications

Inhibits tubulin polymerization, which is essential for cell division.

Anticancer properties

Studied for its potential in treating various types of cancer.

Antifungal and antibacterial activities

Investigated for its potential in developing new drugs.

Research potential

Possesses interesting biological properties, making it a target for further research and potential medical applications.

Upstream product

• 15028-56-5 4-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane 
• 100-39-0 benzyl bromide 
• 252376-73-1 C₁₄H₁₅⁽²⁾H₃O₅ 
• 151121-12-9 acetic acid 2-acetoxy-3-benzyloxy-propyl ester 
• 13071-59-5 3-benzyloxypropan-1,2-diol 
• 75-36-5 acetyl chloride 
• 108-05-4 vinyl acetate 
• 6387-89-9 glycidyl acetate 
• 100-51-6 benzyl alcohol 

Downstream Products

• 17325-86-9 (+)-(S)-1,2-di-O-acetyl-3-O-benzylpropane-1,2,3-triol 
• 151212-86-1 (+)-1-O-acetyl-3-O-benzylpropane-1,2,3-triol 
• 153332-62-8 2,3-dihydro-2-benzyloxymethyl-1,4-dioxino<2,3-b>pyridine 
• 153332-61-7 1-benzyloxy-2-(2-chloro-3-pyridinyloxy)-3-propanol 
• 252376-73-1 C₁₄H₁₅⁽²⁾H₃O₅ 
• 121787-44-8 (-)-1-O-acetyl-3-O-benzylpropane-1,2,3-triol 
• 153332-60-6 1-acetoxy-2-(2-chloro-3-pyridinyloxy)-3-benzyloxypropane 

Relevant articles and documents

MBA-cross-linked poly(N-vinyl-2-pyrrolidone)/ferric chloride macromolecular coordination complex as a novel and recyclable Lewis acid catalyst: Synthesis, characterization, and performance toward for regioselective ring-opening alcoholysis of epoxides

A novel macromolecular-metal coordination complex, MBA-cross-linked PNVP/FeCl3 material was fabricated by immobilization of water intolerant ferric chloride onto the porous cross-linked poly(N-vinyl-2-pyrrolidone) carrier beads as a macromolecular ligand or carrier which was prepared by suspension free-radical copolymerization of N-vinyl-2-pyrrolidone (NVP) and N,N′-methylene bis-acrylamide (MBA) as a crosslinking agent in water. The obtained PNVP/FeCl3 was characterized by UV/vis and FT-IR spectroscopies, TGA, FE-SEM, EDX, and ICP techniques. This heterogenized version of ferric chloride is a convenient and safe alternative to highly water intolerant ferric chloride. The catalytic performance of (PNVP/FeCl3) as an efficient and recyclable polymeric Lewis acid catalyst was appropriately probed in the regio-and stereoselective nucleophilic ring opening of various epoxides with various alcohols in excellent yields with TOF up to 182.48 h?1 without generating any waste. The activity data indicate that this heterogeneous catalyst is very active and could be easily recovered, and reused at least six times without appreciable loss of activity indicating its stability under experimental conditions.

Regio- and enantioselective esterifications of polyoxygenated compounds catalyzed by lipases

The lipase catalyzed esterifications of derivatives of propane-1,2,3-triol and butane 1,2,4-triol in organic solvents have been studied. The influence of several factors (lipase source, organic solvent, additives and structural variations in the substrate

HIGHLY REGIOSELECTIVE RING OPENING OF EPOXIDES WITH ALCOHOLS CATALYZED BY ORGANOTIN PHOSPHATE CONDENSATES

Organotin phosphate condensates proved to catalyze the ring opening reaction of epoxides with alcohols in a highly regioselective manner.