15175-18-5

Basic information

• Product Name: Cyclohexanone, 2-chloro-4-(1,1-dimethylethyl)-, trans-
• CAS NO: 15175-18-5
• Molecular Formula: C10H17ClO
• Molecular Weight: 188.697
• Mol File: 15175-18-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Cyclohexanone, 2-chloro-4-(1,1-dimethylethyl)-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanone, 2-chloro-4-(1,1-dimethylethyl)-, trans-(15175-18-5)
• EPA Substance Registry System: Cyclohexanone, 2-chloro-4-(1,1-dimethylethyl)-, trans-(15175-18-5)

Safety Data

• Hazardous Substances Data: 15175-18-5(Hazardous Substances Data)

Upstream product

• 21862-63-5 trans-4-tert-butylcyclohexanol 
• 66323-98-6 tert-butyl(4-tert-butylcyclohex-1-enyloxy)dimethylsilane 
• 19980-19-9 4-t-butyl-1-trimethylsilyloxy-1-cyclohexene 
• 98-53-3 4-tercbutyl-cyclohexanone 

Downstream Products

• 88589-67-7 (Z)-trans-4-tert-Butyl-2-chlorocyclohexan-1-one oxime 
• 88589-66-6 (E)-trans-4-tert-Butyl-2-chlorocyclohexan-1-one oxime 
• 937-07-5 4-tert-butylcyclohex-2-enone 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 17002-13-0 trans-t-butyl-4 cis-chloro-2 cyclohexanol 
• 62845-83-4 4-(tert-butyl)cyclohex-1-en-1-yl diethyl phosphate 
• 62845-82-3 Phosphoric acid 4-tert-butyl-cyclohex-1-enyl ester dimethyl ester 
• 42974-01-6 (2R*,4S*)-4-(t-butyl)-2-phenyl-1-cyclohexanone 
• 62845-84-5 4-(tert-butyl)cyclohex-1-en-1-yl diisopropyl phosphate 
• 16508-33-1 cis-4-tert-butyl-2-chlorocyclohexanone 

Relevant articles and documents

CONFORMATIONAL EQUILIBRIA IN HALOCYCLOHEXANONES, AN NMR AND SOLVATION STUDY

The conformational equilibrium in 2-chloro-cyclohexanone is measured in thirteen solvents from the 220 MHz 1H NMR spectrum, using the C2-H couplings and chemical shifts and the cis and trans-4-t-butyl-2-chlorocyclohexanones as refere

Direct conversion of alcohols to α-chloro aldehydes and α-chloro ketones

Direct conversion of primary and secondary alcohols into the corresponding α-chloro aldehydes and α-chloro ketones using trichloroisocyanuric acid, serving both as stoichiometric oxidant and α-halogenating reagent, is reported. For primary alcohols, TEMPO has to be added as an oxidation catalyst, and for the transformation of secondary alcohols (TEMPO-free protocol), MeOH as an additive is essential to promote chlorination of the intermediary ketones.

Lewis acid-mediated selective chlorinations of silyl enolate

A new method involving efficient, widely applicable, and highly selective α-chlorination of simple silyl enolate with Lewis acid and an α,α-dichloro-1,3-dicarbonyl controller unit was reported. Diastereoselectivity and enantioselectivity of the reaction were investigated. High reactivity and selectivity were achieved by using α,α-dichlorinated malonic ester. Copyright