1527512-97-5Relevant articles and documents
Novel one-pot multicomponent synthesis of substituted 2,3-dihydro-2-(6-(4- hydroxy-6-methyl-2-oxo-2h-pyran-3-yl)-7h-[1,2,4]triazolo[3,4-b][1,3,4] thiadiazin-3-yl)phthalazine-1,4-diones and substituted 3-[3-(n′- benzylidene-hydrazino)-7h-[1,2,4] triazolo[3,4-b][1,3,4]thiadiazin-6-yl]-4- hydroxy-6-methyl-pyran-2-ones
Thirupaiah, Bade,Vedula, Rajeswar Rao
supporting information, p. 513 - 519 (2014/01/23)
A one-pot procedure has been developed for the synthesis of substituted 2,3-dihydro-2-(6-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-7H-[1,2,4]triazolo[3, 4-b] [1,3,4]thiadiazin-3-yl)phthalazine-1,4-diones by reaction of 3-(2-bromoacetyl)-4-hydroxy-6-methyl-2H-pyran-2-one, 4-amino-5-hydrazino-4H-[1, 2,4]triazole-3-thiol, and phthalic anhydrides in acetic acid medium. Similarly, a one-pot, three-component synthetic procedure has been developed for substituted 3-[3-(N1-benzylidene-hydrazino)-7H-[1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-yl]-4-hydroxy-6-methyl-pyran-2-ones from 3-(2-bromoacetyl)-4-hydroxy-6-methyl-2H-pyran-2-one, 4-amino-5-hydrazino-4H-[1, 2,4]triazole-3-thiol, and various aromatic aldehydes in absolute ethanol and a few drops of glacial acetic acid.
