153454-33-2

Basic information

• Product Name: O-[5'-O-(4,4-dimethoxytrityl)thymidin-3-yl]-O-[3'-O-(4,4-dimethoxytrityl)thymidin-5'-yl]N,N-diisopropylphosphoramidite
• CAS NO: 153454-33-2
• Molecular Weight: 1218.35
• Mol File: 153454-33-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: O-[5'-O-(4,4-dimethoxytrityl)thymidin-3-yl]-O-[3'-O-(4,4-dimethoxytrityl)thymidin-5'-yl]N,N-diisopropylphosphoramidite(CAS DataBase Reference)
• NIST Chemistry Reference: O-[5'-O-(4,4-dimethoxytrityl)thymidin-3-yl]-O-[3'-O-(4,4-dimethoxytrityl)thymidin-5'-yl]N,N-diisopropylphosphoramidite(153454-33-2)
• EPA Substance Registry System: O-[5'-O-(4,4-dimethoxytrityl)thymidin-3-yl]-O-[3'-O-(4,4-dimethoxytrityl)thymidin-5'-yl]N,N-diisopropylphosphoramidite(153454-33-2)

Safety Data

• Hazardous Substances Data: 153454-33-2(Hazardous Substances Data)

Upstream product

• 153413-66-2 O-(5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl) O-(4-nitrophenyl) N,N-diisopropylphosphoramidite 
• 153413-65-1 O,O'-bis-(4-nitrophenyl) N,N-diisopropylphosphoramidite 
• 76054-81-4 3'-O-(4,4'-dimethoxytrityl)thymidine 
• 921-26-6 N,N-diisopropylphosphoramide dichloride 

Downstream Products

• 153413-68-4 C₆₉H₆₇Cl₂N₄O₁₄PS 
• 153413-69-5 S-(2,4-dichlorobenzyl)-5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl 3'-O-(4,4'-dimethoxytrityl)thymidin-5-yl phosphoroselenothioate 
• 153454-34-3 C₆₉H₆₇Cl₂N₄O₁₄PS₂ 
• 153413-67-3 C₆₈H₆₆N₅O₁₇P 

Relevant articles and documents

New phosphitylating reagent in the nucleotide chemistry containing two 4-nitrophenoxy leaving groups. Remarkably fast and clean phosphitylations activated by DBU leading to thio- and seleno-oligonucleotides

A new synthetic approach to modified oligonucleotides based on N,N′-diisopropyl-di-(4-nitrophenyl)phosphoroamidite 1 is described. The procedure involves displacement of either 4-nitrophenoxy or diisopropylamino ligands. The former proceeds very fast in t