1537168-80-1

Basic information

• Product Name: (3S)-1-[5-(3-{[2-(difluoromethoxy)phenyl]methyl}-2-methylimidazo[1,2-a]pyrazin-6-yl)pyrimidin-2-yl]piperidine-3-carboxylic acid
• Synonyms: (3S)-1-[5-(3-{[2-(difluoromethoxy)phenyl]methyl}-2-methylimidazo[1,2-a]pyrazin-6-yl)pyrimidin-2-yl]piperidine-3-carboxylic acid
• CAS NO: 1537168-80-1
• Molecular Weight: 494.501
• Mol File: 1537168-80-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3S)-1-[5-(3-{[2-(difluoromethoxy)phenyl]methyl}-2-methylimidazo[1,2-a]pyrazin-6-yl)pyrimidin-2-yl]piperidine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-1-[5-(3-{[2-(difluoromethoxy)phenyl]methyl}-2-methylimidazo[1,2-a]pyrazin-6-yl)pyrimidin-2-yl]piperidine-3-carboxylic acid(1537168-80-1)
• EPA Substance Registry System: (3S)-1-[5-(3-{[2-(difluoromethoxy)phenyl]methyl}-2-methylimidazo[1,2-a]pyrazin-6-yl)pyrimidin-2-yl]piperidine-3-carboxylic acid(1537168-80-1)

Safety Data

• Hazardous Substances Data: 1537168-80-1(Hazardous Substances Data)

Upstream product

• 1003845-06-4 (2-chloropyrimidin-5-yl)boronic acid 
• 1537169-11-1 6-bromo-3-[2-(difluoromethoxy)benzyl]-2-methylimidazo[1,2-a]pyrazine 
• 498-95-3 (S)-nipecotic acid 

Relevant articles and documents

Imidazopyrazine Derivatives as Modulators of TNF Activity

A series of imidazo[1,2-α]pyrazine derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorder; and oncological disorders.