154079-56-8

Basic information

• Product Name: (2S,3S)-3-diphenylmethylamino-5-phenyl-1,2-pentanediol
• Synonyms: (2S,3S)-3-diphenylmethylamino-5-phenyl-1,2-pentanediol
• CAS NO: 154079-56-8
• Molecular Weight: 361.484
• Mol File: 154079-56-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S,3S)-3-diphenylmethylamino-5-phenyl-1,2-pentanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-3-diphenylmethylamino-5-phenyl-1,2-pentanediol(154079-56-8)
• EPA Substance Registry System: (2S,3S)-3-diphenylmethylamino-5-phenyl-1,2-pentanediol(154079-56-8)

Safety Data

• Hazardous Substances Data: 154079-56-8(Hazardous Substances Data)

Upstream product

• 75553-23-0 (E)-5-phenyl-2-penten-1-ol 
• 91-00-9 Benzhydrylamine 
• 154428-47-4 (2R,3R)-trans-2,3-epoxy-5-phenyl-1-pentanol 

Downstream Products

• 197231-58-6 [(1S,2S)-2,3-Bis-(tert-butyl-dimethyl-silanyloxy)-1-phenethyl-propyl]-carbamic acid tert-butyl ester 
• 197231-57-5 (1S,4'S)-N-tert-butoxycarbonyl-1-(2',2'-dimethyl-[1',3']-dioxolan-4'-yl)-3-phenylpropylamine 
• 799560-32-0 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1-(2-naphthylsulfonyl)-2-pentanol 
• 799560-01-3 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1-(2-naphthylthio)-2-pentanol 
• 799560-28-4 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1-phenylsulfonyl-2-pentanol 
• 799559-90-3 tert-butyl (2S,3S)-2-hydroxy-5-phenyl-1-(phenylthio)pentan-3-ylcarbamate 
• 799560-30-8 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1-methylsulfonyl-2-pentanol 
• 799560-09-1 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1-methylthio-2-pentanol 
• 799559-75-4 (S)-[(S)-1-(tert-butoxycarbonylamino)-3-phenylpropyl]oxirane 
• 799560-43-3 (3S,E)-3-(tert-butoxycarbonylamino)-5-phenyl-1-(2-naphthylsulfonyl)-1-pentene 
• 170111-73-6 (3S)-N-(1-benzenesulfonyl-5-phenyl-pent-1-en-3-yl)carbamic acid tert-butyl ester 
• 170111-71-4 (3S,E)-3-(tert-butoxycarbonylamino)-5-phenyl-1-methylsulfonyl-1-pentene 
• 154079-57-9 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1,2-pentanediol 

Relevant articles and documents

Enantioselective synthesis of (S)-Vigabatrin

An asymmetric synthesis of fully protected (S)-Vigabatrin has been developed. The key intermediate in the sequence is enantiomerically pure N-Boc-5-phenyl-3-amino-1,2-diol 5a, obtained from (E)-5-phenyl-2-penten-1-ol by employing a catalytic Sharpless epo

A short enantioselective synthesis of N-Boc-α-amino acids from epoxy alcohols

A new and efficient enantioselective synthesis of Boc-α-amino acids has been developed. Starting from an enantiomerically enriched epoxy alcohol the sequence involves a regioselective nucleophilic epoxide opening by diphenylmethylamine (benzhydrilamine), hydrogenolysis/ protection of the amino group, and oxidation of the diol moiety.