154079-57-9

Basic information

• Product Name: Carbamic acid, [(1S,2S)-2,3-dihydroxy-1-(2-phenylethyl)propyl]-, 1,1-dimethylethyl ester
• CAS NO: 154079-57-9
• Molecular Formula: C16H25NO4
• Molecular Weight: 295.379
• Mol File: 154079-57-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S,2S)-2,3-dihydroxy-1-(2-phenylethyl)propyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S,2S)-2,3-dihydroxy-1-(2-phenylethyl)propyl]-, 1,1-dimethylethyl ester(154079-57-9)
• EPA Substance Registry System: Carbamic acid, [(1S,2S)-2,3-dihydroxy-1-(2-phenylethyl)propyl]-, 1,1-dimethylethyl ester(154079-57-9)

Safety Data

• Hazardous Substances Data: 154079-57-9(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 75553-23-0 (E)-5-phenyl-2-penten-1-ol 
• 91-00-9 Benzhydrylamine 
• 154428-47-4 (2R,3R)-trans-2,3-epoxy-5-phenyl-1-pentanol 
• 154079-56-8 (2S,3S)-3-diphenylmethylamino-5-phenyl-1,2-pentanediol 

Downstream Products

• 158807-52-4 methyl (3S)-3-(N-tert-butoxycarbonylamino)-5-phenylpentanoate 
• 218608-84-5 (S)-3-<<(tert-butoxy)carbonyl>amino>-5-phenylpentanoic acid 
• 158807-48-8 [(S)-1-(2-Hydroxy-ethyl)-3-phenyl-propyl]-carbamic acid tert-butyl ester 
• 158807-45-5 ((S)-1-Phenethyl-allyl)-carbamic acid tert-butyl ester 
• 799560-32-0 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1-(2-naphthylsulfonyl)-2-pentanol 
• 799560-01-3 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1-(2-naphthylthio)-2-pentanol 
• 799560-28-4 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1-phenylsulfonyl-2-pentanol 
• 799559-90-3 tert-butyl (2S,3S)-2-hydroxy-5-phenyl-1-(phenylthio)pentan-3-ylcarbamate 
• 799560-30-8 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1-methylsulfonyl-2-pentanol 
• 799560-09-1 (2S,3S)-3-(tert-butoxycarbonylamino)-5-phenyl-1-methylthio-2-pentanol 
• 799560-43-3 (3S,E)-3-(tert-butoxycarbonylamino)-5-phenyl-1-(2-naphthylsulfonyl)-1-pentene 
• 170111-73-6 (3S)-N-(1-benzenesulfonyl-5-phenyl-pent-1-en-3-yl)carbamic acid tert-butyl ester 
• 170111-71-4 (3S,E)-3-(tert-butoxycarbonylamino)-5-phenyl-1-methylsulfonyl-1-pentene 
• 799559-75-4 (S)-[(S)-1-(tert-butoxycarbonylamino)-3-phenylpropyl]oxirane 

Relevant articles and documents

Enantiodivergent, catalytic asymmetric synthesis of γ-amino vinyl sulfones

A set of diversely substituted N-Boc-γ-amino vinyl sulfones has been prepared by a four-step procedure from readily available, highly enantiopure anti-N-Boc-3-amino-1,2-alkanediols. This new route, which does not depend on the accessibility of α-amino acids as starting materials, is noteworthy for its efficiency, for its generality, and for the fact that both enantiomers of a given γ-amino vinyl sulfone can be obtained with equal ease.

A short enantioselective synthesis of N-Boc-α-amino acids from epoxy alcohols

A new and efficient enantioselective synthesis of Boc-α-amino acids has been developed. Starting from an enantiomerically enriched epoxy alcohol the sequence involves a regioselective nucleophilic epoxide opening by diphenylmethylamine (benzhydrilamine), hydrogenolysis/ protection of the amino group, and oxidation of the diol moiety.