15421-91-7

Basic information

• Product Name: Benzenecarboximidamide, N-butyl-
• CAS NO: 15421-91-7
• Molecular Formula: C11H16N2
• Molecular Weight: 176.261
• Mol File: 15421-91-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzenecarboximidamide, N-butyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarboximidamide, N-butyl-(15421-91-7)
• EPA Substance Registry System: Benzenecarboximidamide, N-butyl-(15421-91-7)

Safety Data

• Hazardous Substances Data: 15421-91-7(Hazardous Substances Data)

Upstream product

• 5873-90-5 methyl benzimidate hydrochloride 
• 109-73-9 N-butylamine 
• 57767-07-4 N-methyl-N-phenylbenzimidamide 
• 7471-86-5 methyl benzimidate 
• 2782-40-3 N-butylbenzamide 
• 618-39-3 benzamidin 
• 1246287-59-1 C₁₄H₁₄N₄O₂ 
• 100-47-0 benzonitrile 
• 825-60-5 benzimidic acid ethyl ester 
• 98-88-4 benzoyl chloride 

Downstream Products

• 52120-10-2 N,N'-di-n-butyl-benzamidine 
• 1775-70-8 N-Butyl-N'-benzylbenzamidin 
• 198065-92-8 1-(1-Butyl)-2-phenylimidazole-5-carboxaldehyde 
• 1359955-88-6 ethyl 1-n-butyl-2-phenyl-1,6-dihydropyrimidine-5-carboxylate 
• 1372861-24-9 N-butyl-N-[2-ethoxycarbonyl-3-(methylamino)prop-2-en-1-yl]benzamide 
• 1359955-78-4 ethyl 1-butyl-4-dimethylamino-2-phenyl-1,4,5,6-tetrahydropyrimidine-5-carboxylate 
• 1359955-72-8 1-dimethylamino-3-phenyl-2,4-diaza-1,3-octadiene 
• 439571-74-1 butyl(1-butyl-2-phenyl-4,5,6-trihydrocyclopentyl[3,2-d]imidazol-6-yl)amine 
• 439571-73-0 1-butyl-2-phenyl-4,5-dihydrocyclopenty[1,2-d]imidazol-6-ol 
• 1354728-29-2 C₁₆H₁₉ClN₂ 
• 439571-66-1 1-(1-Butyl)-2-phenyl-5-hydroxymethylimidazole 
• 439571-69-4 1-Butyl-2-phenyl-5-(1-hydroxyethyl)imidazole 
• 439557-47-8 4-{[butyl(1-butyl-2-phenyl(4,5,6-trihydrocyclopenta[3,2-d]imidazol-6-yl))amino]methyl}-3-chlorophenol 
• 439557-44-5 1-butyl-2-phenyl-5-(1-[N-[3,4-methylenedioxyphenylmethyl]-N-(phenylmethyl)amino]ethyl)imidazole 

Relevant articles and documents

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Acid-catalyzed synthesis of imidazole derivatives via N-phenylbenzimidamides and sulfoxonium ylides cyclization

A straightforward method to synthesize imidazole derivatives from amidines and sulfoxonium ylides catalyzed by acids is reported in this study. Specifically, catalyzed by trifluoroacetic acid in DCE solvents can improve synthesis efficiency under metal-fr

Intramolecular alkene hydroamination and degradation of amidines: Divergent behavior of rare earth metal amidinate intermediates

Direct N-H addition of amidines to alkenes is a highly valuable but challenging transformation that remains elusive. Now, the intramolecular hydroamidination of N-alkenylamidines is achieved by using a rare earth catalyst, which provides an efficient and atom-economical approach for substituted imidazolines and tetrahydropyrimidines. Moreover, a mild and efficient method for the catalytic degradation of amidines to give amines and nitriles is also developed. Additionally, amidine reconstruction followed by an intramolecular alkene hydroamidination strategy for the synthesis of substituted imidazolines and tetrahydropyrimidines from secondary enamines and inactive amidines has also been established, which may circumvent the need for some unavailable starting materials. The mechanistic studies prove that these reactions proceed via a key lanthanide amidinate intermediate that can undergo substrate- and amine-controlled chemodivergent transformations: intramolecular alkene insertion, nitrile extrusion, amidinate reconstruction, or a combination of the reactions. The results presented here not only demonstrate the synthetic potential and versatility of alkene hydroamidination with substrates, but also provide a good insight into the factors that promote or deter the hydroamidination of alkenes.