15451-14-6

Basic information

• Product Name: 3-DIMETHYLAMINO-2,2-DIMETHYLPROPIONALDEHYDE
• Synonyms: TIMTEC-BB SBB007757;3-(dimethylamino)-2,2-dimethyl-propana;3-(Dimethylamino)-2,2-dimethylpropanal;Propanal, 3-(dimethylamino)-2,2-dimethyl-;3-DIMETHYLAMINO-2,2-DIMETHYLPROPIONALDEHYDE;2,2-DIMETHYL-3-(DIMETHYLAMINO)-PROPIONALDEHYDE;Einecs 239-468-8
• CAS NO: 15451-14-6
• Molecular Formula: C₇H₁₅NO
• Molecular Weight: 129.2
• EINECS: 239-468-8
• Mol File: 15451-14-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 151.1 °C at 760 mmHg
• Flash Point: 34.2 °C
• Appearance: /
• Density: 0.868 g/cm³
• Vapor Pressure: 3.72mmHg at 25°C
• CAS DataBase Reference: 3-DIMETHYLAMINO-2,2-DIMETHYLPROPIONALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-DIMETHYLAMINO-2,2-DIMETHYLPROPIONALDEHYDE(15451-14-6)
• EPA Substance Registry System: 3-DIMETHYLAMINO-2,2-DIMETHYLPROPIONALDEHYDE(15451-14-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 15451-14-6(Hazardous Substances Data)

Usage

Description

3-Dimethylamino-2,2-dimethylpropionaldehyde is an organic compound with the chemical formula C8H17NO. It is a derivative of propionaldehyde, featuring a dimethylamino group and two methyl groups attached to the carbon chain. 3-DIMETHYLAMINO-2,2-DIMETHYLPROPIONALDEHYDE is known for its potential applications in various industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
3-Dimethylamino-2,2-dimethylpropionaldehyde is used as a chemical intermediate for the synthesis of SYK inhibitors. These inhibitors are designed to treat SYK-mediated diseases, which involve the overactivation of the spleen tyrosine kinase (SYK) enzyme. By inhibiting this enzyme, the compound can potentially help in managing and treating various conditions associated with SYK overactivity.

InChI:InChI=1/C7H15NO/c1-7(2,6-9)5-8(3)4/h6H,5H2,1-4H3/p+1

Upstream product

• 50-00-0 formaldehyd 
• 107-97-1 sarcosine 
• 78-84-2 isobutyraldehyde 
• 6906-32-7 N,N,2-Trimethyl-1-propen-1-amin 
• 123618-06-4 (4S,5R)-3,4-dimethyl-5-phenyl-1,3-oxazolidine 
• 13657-16-4 3-benzyl-1,3-oxazolidine 
• 27970-32-7 3-methyl-1,3-oxazolidine 
• 30354-18-8 N,N-dimethyl(methylene)ammonium chloride 
• 506-59-2 N,N-dimethylammonium chloride 
• 1741-41-9 isobutyraldehyde diethyl acetal 

Downstream Products

• 14389-03-8 Dimethylamino-pivaldehyd-tosylhydrazon 
• 1429442-69-2 (R)-N-((S)-4-(dimethylamino)-3,3-dimethyl-1-morpholino-1-oxobutan-2-yl)-2,4,6-triisopropylbenzenesulfinamide 
• 1429442-63-6 (R)-N-(3-(dimethylamino)-2,2-dimethylpropylidene)-2,4,6-triisopropylbenzenesulfinamide 
• 1333388-31-0 C₂₁H₂₅NO₄ 
• 1313281-55-8 benzyl[3-hydroxy-2,2-dimethyl-3-(dimethoxyphosphoryl)propyl]dimethylammonium bromide 
• 16911-23-2 (2,2-dimethyl-4-phenyl-3-butenyl)dimethylamine 
• 15451-16-8 1-Chlor-2,2-dimethyl-3-dimethylamino-1-phenylpropan 
• 127753-35-9 3-dimethylamino-2,2-dimethyl-propionic acid 
• 19059-68-8 3-(dimethylamino)-2,2-dimethylpropan-1-ol 
• 15101-88-9 [2,2-Dimethyl-3-(3-phenyl-indan-1-yl)-propyl]-dimethyl-amine 
• 53369-71-4 N,N,2,2-tetramethyl-1,3-propanediamine 
• 15451-15-7 1-Phenyl-2,2-dimethyl-3-dimethylamino-1-propanol 

Relevant articles and documents

Three Ways Aliphatic Aldehydes React with Nonstabilized Azomethine Ylides

Aliphatic aldehydes readily react with nonstabilized azomethine ylides in one of the three ways to give oxazolidines, pyrrolidines, or Mannich bases, depending on the structure of the starting compound and the reaction conditions. The use of N -(methoxymethyl)- N -[(trimethylsilyl)methyl]benzylamine in DMF provided 5-alkyloxazolidines in 40-97percent yields. On the other hand, three-component reactions of aliphatic aldehydes bearing one α-hydrogen with N -methyl(benzyl)glycine and formaldehyde gives Mannich bases in yields of 47-98percent. A similar reaction of aldehydes bearing branched alkyl groups and two hydrogen atoms at the α-position proceeds as a domino process that gives 3-alkyl-3-formylpyrrolidines in yields of 34-93percent.

SECONDARY AMINOSILANES

The present disclosure invention relates to novel secondary aminosilanes, a method for producing same, and the use thereof. The secondary aminosilanes can be produced from readily available reactants in a simple manner. The secondary aminosilanes are characterized for example by a low viscosity and are well suited for producing silane-functional polymers that have a low viscosity, fast curing, and good thermal stability.

Seven-Membered Rings by 1,5-Cycloadditions, VI. - 7-Aminoperhydro-1,4-oxazepines and -diazepines

3-Alkyl-1,3-oxazolidines 2 react with enamines 1 in the presence of trifluoroacetic acid to give 7-dialkylaminoperhydro-1,4-oxazepines 3. 1,3-Dimethyl-1,3-imidazolidine (2d) reacts with 4-(2-methyl-1-propenyl)morpholine (1a) to give 1,4,6,6-tetramethyl-7-morpholino-2,3,4,5,6,7-hexahydro-1H-1,4-diazepine (3m).