154639-01-7

Basic information

• Product Name: (rac)-4-(1-hydroxyethyl)-2-chlorophenol
• Synonyms: (rac)-4-(1-hydroxyethyl)-2-chlorophenol
• CAS NO: 154639-01-7
• Molecular Weight: 172.611
• Mol File: 154639-01-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (rac)-4-(1-hydroxyethyl)-2-chlorophenol(CAS DataBase Reference)
• NIST Chemistry Reference: (rac)-4-(1-hydroxyethyl)-2-chlorophenol(154639-01-7)
• EPA Substance Registry System: (rac)-4-(1-hydroxyethyl)-2-chlorophenol(154639-01-7)

Safety Data

• Hazardous Substances Data: 154639-01-7(Hazardous Substances Data)

Upstream product

• 93453-79-3 1-(4-hydroxyphenyl)ethanol 
• 2892-29-7 3-chloro-4-hydroxy-acetophenone 

Relevant articles and documents

Ammonium Salt-Catalyzed Highly Practical Ortho-Selective Monohalogenation and Phenylselenation of Phenols: Scope and Applications

An ortho-selective ammonium chloride salt-catalyzed direct C-H monohalogenation of phenols and 1,1′-bi-2-naphthol (BINOL) with 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) as the chlorinating agent has been developed. The catalyst loading was low (down to 0.01 mol %) and the reaction conditions were very mild. A wide range of substrates including BINOLs were compatible with this catalytic protocol. Chlorinated BINOLs are useful synthons for the synthesis of a wide range of unsymmetrical 3-aryl BINOLs that are not easily accessible. In addition, the same catalytic system can facilitate the ortho-selective selenylation of phenols.