154775-01-6

Basic information

• Product Name: (R)-1-(meta-trifluoromethylphenyl) 3-tosyloxy 2-propanol
• Synonyms: (R)-1-(meta-trifluoromethylphenyl) 3-tosyloxy 2-propanol
• CAS NO: 154775-01-6
• Molecular Weight: 374.381
• Mol File: 154775-01-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-(meta-trifluoromethylphenyl) 3-tosyloxy 2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(meta-trifluoromethylphenyl) 3-tosyloxy 2-propanol(154775-01-6)
• EPA Substance Registry System: (R)-1-(meta-trifluoromethylphenyl) 3-tosyloxy 2-propanol(154775-01-6)

Safety Data

• Hazardous Substances Data: 154775-01-6(Hazardous Substances Data)

Upstream product

• 113048-70-7 (1S,2S)-1-(meta-trifluoromethylphenyl) 1,2-epoxy-3-propanol 
• 113048-69-4 (E)-3-(3-trifluoromethylphenyl)prop-2-en-1-ol 
• 98-59-9 p-toluenesulfonyl chloride 
• 154902-50-8 (R)-1-(meta-trifluoromethylphenyl) 2,3-propanediol 
• 154309-48-5 1-<3-(trifluoromethyl)phenyl>prop-2-en-1-ol 

Downstream Products

• 41320-75-6 meta-trifluoromethylphenyl-propane 
• 78573-45-2 3-[3-(trifluoromethyl)phenyl]propan-1-ol 
• 135561-75-0 (S)-1-[(3′-trifluoromethyl)phenyl]-2-propanol 

Relevant articles and documents

Asymmetric syntheses of (S)-Fenfluramine using Sharpless Epoxidation Methods

We describe one synthesis of (S)-fenfluramine and several syntheses of its precursors (R)- and (S)-1-(meta-trifluoromethylphenyl)propan-2-ols.They were obtained from the asymmetric epoxidation of the primary allylic alcohol 5 and from the kinetic resolution with asymmetric epoxidation of teh secondary allylic alcohol 6.