155204-28-7 Usage
Description
WAY 100634 is a selective antagonist of the serotonin 5-HT1A receptor, which is a major metabolite of WAY 100635 (W49865), a dopamine D4 receptor. It is a light yellow solid and has been widely studied for its potential applications in various fields due to its unique chemical properties and receptor specificity.
Uses
Used in Pharmaceutical Industry:
WAY 100634 is used as a research chemical for the investigation of the serotonin 5-HT1A receptor's role in various physiological and pathological processes. Its high selectivity for the 5-HT1A receptor makes it a valuable tool in understanding the receptor's function and its potential as a therapeutic target.
Used in Neuropharmacology:
In the field of neuropharmacology, WAY 100634 is used as a selective antagonist to study the effects of serotonin on the central nervous system. This helps researchers to better understand the role of serotonin in mood regulation, anxiety, and other neurological disorders.
Used in Antidepressant Research:
WAY 100634 is used as a research compound in the development of novel antidepressant medications. By blocking the 5-HT1A receptor, it can help researchers identify new pathways and targets for the treatment of depression and other mood disorders.
Used in Drug Delivery Systems:
Similar to gallotannin, WAY 100634 can also be incorporated into drug delivery systems to improve its bioavailability and therapeutic outcomes. These systems can be tailored to specific applications, such as targeting specific cell types or tissues, to enhance the effectiveness of WAY 100634 in treating various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 155204-28-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,2,0 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 155204-28:
(8*1)+(7*5)+(6*5)+(5*2)+(4*0)+(3*4)+(2*2)+(1*8)=107
107 % 10 = 7
So 155204-28-7 is a valid CAS Registry Number.
155204-28-7Relevant articles and documents
Structural Insights into 5-HT1A/D4 Selectivity of WAY-100635 Analogues: Molecular Modeling, Synthesis, and in Vitro Binding
Dilly, Sébastien,Liégeois, Jean-Fran?ois
, p. 1324 - 1331 (2016/08/02)
The resurgence of interest in 5-HT1A receptors as a therapeutic target requires the existence of highly selective 5-HT1A ligands. To date, WAY-100635 has been the prototypical antagonist of these receptors. However, this compound als
NOVEL SYNTHESIS METHOD
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Page/Page column 32-33, (2013/04/10)
The present invention relates to a method of making compounds having affinity for the 1 A subtype of the serotonin receptor, i.e. 5HT1A. The method of the present invention provides advantages over the known methods of synthesis. The compounds
EFFICIENT SYNTHETIC METHOD OF 18F-MEFWAY PRECURSOR
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Page/Page column 8, (2012/06/16)
The present invention relates a novel method for preparing an 18F-mefway precursor. The present invention provides an efficient synthetic method of an 18F-mefway precursor, which comprises an improved the acid chloride coupling react