155252-34-9

Basic information

• Product Name: Podophyllotoxin, derivative of
• Synonyms: Podophyllotoxin, derivative of
• CAS NO: 155252-34-9
• Molecular Formula: C₂₂H₂₁N₃O₇
• Molecular Weight: 0
• Mol File: 155252-34-9.mol
• Article Data: 30

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Podophyllotoxin, derivative of(CAS DataBase Reference)
• NIST Chemistry Reference: Podophyllotoxin, derivative of(155252-34-9)
• EPA Substance Registry System: Podophyllotoxin, derivative of(155252-34-9)

Safety Data

• Hazardous Substances Data: 155252-34-9(Hazardous Substances Data)

Upstream product

• 7401-22-1 9-Chloro-9-desoxypodophyllotoxin 
• 518-28-5 podofilox 
• 4375-07-9 epipodophyllotoxin 
• 908355-89-5 Methanesulfonic acid (5R,5aR,8aR,9R)-8-oxo-9-(3,4,5-trimethoxy-phenyl)-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl ester 

Downstream Products

• 1092371-34-0 9-(4-phenylaminomethyl-[1,2,3]triazol-1-yl)-5-(3,4,5-trimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 1092371-36-2 9-{4-[(2-chloro-phenylamino)-methyl]-[1,2,3]triazol-1-yl}-5-(3,4,5-trimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 1092371-37-3 9-[4-(p-tolylamino-methyl)-[1,2,3]triazol-1-yl]-5-(3,4,5-trimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 1092371-30-6 9-{4-[(3-chloro-phenylamino)-methyl]-[1,2,3]triazol-1-yl}-5-(3,4,5-trimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 1092371-31-7 9-{4-[(3-chloro-phenylamino)-methyl]-[1,2,3]triazol-1-yl}-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 1092371-28-2 9-[4-(o-tolylamino-methyl)-[1,2,3]triazol-1-yl]-5-(3,4,5-trimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 1579998-69-8 C₃₉H₄₁N₂O₁₁ 
• 1579998-72-3 C₃₆H₄₃N₂O₁₁ 
• 1579998-66-5 C₃₈H₄₅N₂O₁₁ 
• 1579998-70-1 C₄₀H₄₃N₂O₁₂ 
• 1579998-73-4 C₄₀H₄₃N₂O₁₁ 
• 1579998-67-6 C₃₇H₃₉N₂O₁₂ 
• 1579998-71-2 C₄₀H₄₁N₂O₁₃ 
• 1579998-74-5 C₃₇H₄₇N₂O₁₁ 

Relevant articles and documents

Synthesis of novel 4β-(1,2,3-triazol-1-yl) podophyllotoxins as potential antitumor drugs

The synthesis, characterization and in vitro antitumor activity of two novel podophyllotoxins, 4β-(5-methyl-1,2,3-triazol-1-yl)podophyllotoxin (5) and 4β-(5-phenyl-1,2,3-triazol-1-yl)podophyllotoxin (6), are described.

One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH2SO3H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents

A facile one-pot method for the synthesis of novel podophyllotoxin-thiourea congeners has been developed by using NH2SO3H/NaI system. Interestingly, 4β-azido podophyllotoxin reduction with concomitant aryl isothiocyanates coupling un

Synthesis and Anticancer Activity of Podophyllotoxin Derivatives

Two series of podophyllotoxin derivatives were synthesized by addition of a 4β-sulfanilamide to or substitution of a 4β-amide into podophyllotoxin. Their cytotoxicities were evaluated against four human cancer cell lines (A549, HeLa, MCF-7, and PC-3). Inv

Synthesis and Cytotoxicity of Heterocyclic Amine Derivatives of Podophyllotoxin

A series of amine podophyllotoxin derivatives was designed and synthesized by aldehydes reacting with 4β-amino-desoxypodophyllotoxin or 4′-demethyldesoxypodophyllotoxin. The MTT assay was used to test the cytotoxic activity of 11 target compounds on HeLa