155252-35-0

Basic information

• Product Name: 4β-amino-4-deoxypodophyllotoxin
• Synonyms: 4β-amino-4-deoxypodophyllotoxin
• CAS NO: 155252-35-0
• Molecular Weight: 413.427
• Mol File: 155252-35-0.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: 4β-amino-4-deoxypodophyllotoxin(CAS DataBase Reference)
• NIST Chemistry Reference: 4β-amino-4-deoxypodophyllotoxin(155252-35-0)
• EPA Substance Registry System: 4β-amino-4-deoxypodophyllotoxin(155252-35-0)

Safety Data

• Hazardous Substances Data: 155252-35-0(Hazardous Substances Data)

Upstream product

• 908355-89-5 Methanesulfonic acid (5R,5aR,8aR,9R)-8-oxo-9-(3,4,5-trimethoxy-phenyl)-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl ester 
• 4375-07-9 epipodophyllotoxin 
• 748151-22-6 4-β-(2''-chloroacetamido)podophyllotoxin 
• 518-28-5 podofilox 
• 106636-74-2 4β-bromo-4-desoxypodophyllotoxin 
• 197016-28-7 (5R,5aR,8aS)-9-Azido-5-(3,4,5-trimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 155252-34-9 4β-azido-4-deoxypodophyllotoxin 

Downstream Products

• 1061717-11-0 4β-((1-(benzo[1,3]dioxol-5-ylmethyl)-indol-3-yl)-glyoxylamide)-4-desoxypodophyllotoxin 
• 1061717-14-3 4β-((2-methyl-indol-3-yl)-glyoxylamide)-4-desoxypodophyllotoxin 
• 1061717-19-8 4β-((6-methoxy-indol-3-yl)-glyoxylamide)-4-desoxypodophyllotoxin 
• 1061717-17-6 4β-((5-methoxy-indol-3-yl)-glyoxylamide)-4-desoxypodophyllotoxin 
• 1061717-16-5 4β-((6-fluoro-indol-3-yl)-glyoxylamide)-4-desoxypodophyllotoxin 
• 1061717-12-1 4β-((5-bromo-indol-3-yl)-glyoxylamide)-4-desoxypodophyllotoxin 
• 1000206-52-9 4β-((1-(4-chlorobenzyl)-indol-3-yl)-glyoxylamide)-4-desoxypodophyllotoxin 
• 1244966-36-6 C₃₁H₂₈N₂O₁₂ 
• 1244966-35-5 C₃₁H₂₉NO₁₀ 
• 1357098-90-8 4β-[2-(4-[(E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propenyl]phenoxy)acetamido]-4-deoxypodophyllotoxin 
• 1357099-06-9 4β-[2-(2-methoxy-4-[(E)-3-(4-methoxyphenyl)-3-oxo-1-propenyl]phenoxy)acetamido]-4-deoxypodophyllotoxin 

Relevant articles and documents

Click chemistry-assisted synthesis of triazolo linked podophyllotoxin conjugates as tubulin polymerization inhibitors

A series of new triazolo linked 4β-amidopodophyllotoxin conjugates (9a-l) were synthesized using click chemistry and evaluated for their antitumor activity against four human cancer cell lines. Among them, two compounds (9c and 9j) showed significant anti

Synthesis and Anticancer Activity of Podophyllotoxin Derivatives

Two series of podophyllotoxin derivatives were synthesized by addition of a 4β-sulfanilamide to or substitution of a 4β-amide into podophyllotoxin. Their cytotoxicities were evaluated against four human cancer cell lines (A549, HeLa, MCF-7, and PC-3). Inv

4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer

Topoisomerases (topo-I and topo-II) have occupied a significant role in DNA replication, transcription, and are a promising set of antitumor targets. In the present approach, a series of new 4β-amidotriazole linked podophyllotoxin derivatives (10a-i and 1